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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
13.64
Human Site:
S342
Identified Species:
18.75
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
S342
T
P
P
N
P
A
R
S
L
F
A
K
V
T
K
Chimpanzee
Pan troglodytes
XP_513131
442
49225
Q159
S
L
S
L
P
A
R
Q
L
L
A
A
I
L
R
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
S342
T
P
P
N
P
A
R
S
L
F
A
K
V
T
K
Dog
Lupus familis
XP_532604
646
71462
I342
T
P
L
N
P
A
R
I
L
F
V
K
V
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
S343
T
P
P
N
P
A
R
S
L
F
A
K
V
T
K
Rat
Rattus norvegicus
Q9R011
615
68782
S311
T
P
P
N
P
A
R
S
L
F
A
K
V
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
N471
H
L
S
S
P
A
K
N
F
F
K
K
A
A
A
Chicken
Gallus gallus
XP_422425
639
71988
L326
A
P
N
P
A
K
S
L
F
A
K
V
T
K
T
Frog
Xenopus laevis
P70032
598
68193
P313
P
T
T
C
L
T
V
P
P
R
F
S
I
A
P
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
K323
N
P
P
S
P
A
K
K
F
F
T
K
M
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
P295
S
S
C
L
T
M
A
P
R
I
G
S
N
D
T
Honey Bee
Apis mellifera
XP_396707
575
66141
R294
S
C
L
T
M
A
P
R
L
D
M
L
E
M
H
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
E315
N
D
D
E
Y
A
E
E
N
V
S
P
S
G
T
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
V303
A
P
R
F
Q
V
P
V
S
S
G
R
R
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
Q317
P
S
T
S
Y
L
N
Q
F
A
S
P
E
N
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
L158
S
D
F
G
L
S
A
L
R
E
S
K
Q
Q
D
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
Q363
F
E
D
I
P
E
E
Q
S
L
V
N
F
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
33.3
100
80
N.A.
100
100
N.A.
26.6
6.6
0
46.6
N.A.
0
13.3
6.6
6.6
P-Site Similarity:
100
53.3
100
80
N.A.
100
100
N.A.
46.6
6.6
6.6
66.6
N.A.
6.6
20
13.3
13.3
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
6
59
12
0
0
12
30
6
6
18
6
% A
% Cys:
0
6
6
6
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
12
0
0
0
0
0
0
6
0
0
0
6
12
% D
% Glu:
0
6
0
6
0
6
12
6
0
6
0
0
12
0
0
% E
% Phe:
6
0
6
6
0
0
0
0
24
42
6
0
6
0
0
% F
% Gly:
0
0
0
6
0
0
0
0
0
0
12
0
0
6
0
% G
% His:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% H
% Ile:
0
0
0
6
0
0
0
6
0
6
0
0
12
0
0
% I
% Lys:
0
0
0
0
0
6
12
6
0
0
12
48
0
12
36
% K
% Leu:
0
12
12
12
12
6
0
12
42
12
0
6
0
6
6
% L
% Met:
0
0
0
0
6
6
0
0
0
0
6
0
6
6
0
% M
% Asn:
12
0
6
30
0
0
6
6
6
0
0
6
6
6
0
% N
% Pro:
12
48
30
6
53
0
12
12
6
0
0
12
0
6
6
% P
% Gln:
0
0
0
0
6
0
0
18
0
0
0
0
6
6
0
% Q
% Arg:
0
0
6
0
0
0
36
6
12
6
0
6
6
0
6
% R
% Ser:
24
12
12
18
0
6
6
24
12
6
18
12
6
0
6
% S
% Thr:
30
6
12
6
6
6
0
0
0
0
6
0
6
30
18
% T
% Val:
0
0
0
0
0
6
6
6
0
6
12
6
30
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _