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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
21.52
Human Site:
S350
Identified Species:
29.58
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
S350
L
F
A
K
V
T
K
S
L
F
G
R
K
K
K
Chimpanzee
Pan troglodytes
XP_513131
442
49225
A167
L
L
A
A
I
L
R
A
S
P
R
D
R
P
S
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
S350
L
F
A
K
V
T
K
S
L
F
G
R
K
K
N
Dog
Lupus familis
XP_532604
646
71462
S350
L
F
V
K
V
T
K
S
L
F
G
R
K
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
S351
L
F
A
K
V
T
K
S
L
F
G
R
K
K
N
Rat
Rattus norvegicus
Q9R011
615
68782
S319
L
F
A
K
V
T
K
S
L
F
G
R
R
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
A479
F
F
K
K
A
A
A
A
L
F
G
G
K
K
E
Chicken
Gallus gallus
XP_422425
639
71988
L334
F
A
K
V
T
K
T
L
F
R
K
K
K
P
K
Frog
Xenopus laevis
P70032
598
68193
S321
P
R
F
S
I
A
P
S
T
I
D
Q
S
L
R
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
S331
F
F
T
K
M
A
K
S
L
F
G
K
K
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
I303
R
I
G
S
N
D
T
I
E
D
S
M
H
R
K
Honey Bee
Apis mellifera
XP_396707
575
66141
N302
L
D
M
L
E
M
H
N
Q
R
K
P
L
S
E
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
I323
N
V
S
P
S
G
T
I
D
Q
R
G
P
H
Q
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
L311
S
S
G
R
R
P
L
L
E
V
N
G
Q
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
V325
F
A
S
P
E
N
S
V
K
V
P
S
Q
P
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
G166
R
E
S
K
Q
Q
D
G
L
L
H
T
T
C
G
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
C371
S
L
V
N
F
K
D
C
M
E
K
S
L
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
13.3
93.3
93.3
N.A.
93.3
86.6
N.A.
46.6
13.3
6.6
60
N.A.
6.6
6.6
0
0
P-Site Similarity:
100
40
93.3
93.3
N.A.
93.3
93.3
N.A.
60
20
26.6
73.3
N.A.
13.3
20
13.3
20
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
30
6
6
18
6
12
0
0
0
0
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
6
0
0
0
0
0
6
0
% C
% Asp:
0
6
0
0
0
6
12
0
6
6
6
6
0
6
0
% D
% Glu:
0
6
0
0
12
0
0
0
12
6
0
0
0
0
18
% E
% Phe:
24
42
6
0
6
0
0
0
6
42
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
6
0
6
0
0
42
18
0
0
6
% G
% His:
0
0
0
0
0
0
6
0
0
0
6
0
6
6
0
% H
% Ile:
0
6
0
0
12
0
0
12
0
6
0
0
0
0
0
% I
% Lys:
0
0
12
48
0
12
36
0
6
0
18
12
42
42
24
% K
% Leu:
42
12
0
6
0
6
6
12
48
6
0
0
12
12
6
% L
% Met:
0
0
6
0
6
6
0
0
6
0
0
6
0
0
0
% M
% Asn:
6
0
0
6
6
6
0
6
0
0
6
0
0
0
12
% N
% Pro:
6
0
0
12
0
6
6
0
0
6
6
6
6
18
0
% P
% Gln:
0
0
0
0
6
6
0
0
6
6
0
6
12
0
6
% Q
% Arg:
12
6
0
6
6
0
6
0
0
12
12
30
12
6
6
% R
% Ser:
12
6
18
12
6
0
6
42
6
0
6
12
6
6
18
% S
% Thr:
0
0
6
0
6
30
18
0
6
0
0
6
6
0
0
% T
% Val:
0
6
12
6
30
0
0
6
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _