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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLK3 All Species: 4.24
Human Site: S408 Identified Species: 5.83
UniProt: Q9H4B4 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H4B4 NP_004064.2 646 71629 S408 V E T A P E D S S P R G T L A
Chimpanzee Pan troglodytes XP_513131 442 49225 K225 T K S L F G R K K K K S K N H
Rhesus Macaque Macaca mulatta XP_001099497 647 71861 D408 L V E T A P E D S S P R G T L
Dog Lupus familis XP_532604 646 71462 S408 A E T A P E D S S P R G T L A
Cat Felis silvestris
Mouse Mus musculus Q60806 631 69994 G409 S G D G F E E G L T V A T V V
Rat Rattus norvegicus Q9R011 615 68782 D377 L V E T A A E D S S P R G T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507288 794 90557 V537 Q P P N M T V V K S G A P A T
Chicken Gallus gallus XP_422425 639 71988 E392 S P V E T L V E E T S R K S T
Frog Xenopus laevis P70032 598 68193 N379 L Q Q L T C L N A V K P S E R
Zebra Danio Brachydanio rerio NP_958465 644 72571 G389 T V Q L A S S G P L D T P A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52304 576 66955 Q361 D I E S L Y Q Q L T N L I N G
Honey Bee Apis mellifera XP_396707 575 66141 L360 L Q T L R E Q L S A V L K A K
Nematode Worm Caenorhab. elegans Q9N2L7 632 72053 P381 V N D L L A T P T A D I D D A
Sea Urchin Strong. purpuratus XP_784826 587 66895 K369 L T S V V A A K P S E K A D I
Poplar Tree Populus trichocarpa
Maize Zea mays P0C8M8 626 70215 L383 H T N E N V V L T S Q L D R H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJ54 439 50149 I224 L V E M Y R K I T K G E F K C
Baker's Yeast Sacchar. cerevisiae P32562 705 81013 E429 G T K Q K Y K E V V D I E A Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.4 98.4 92.2 N.A. 91 89.7 N.A. 44.3 65.7 40.2 58.6 N.A. 36.8 36.6 35.7 40
Protein Similarity: 100 67.9 98.6 94.8 N.A. 93.5 92.4 N.A. 57.8 80.6 58.5 76.9 N.A. 55.8 56.5 55.1 58.9
P-Site Identity: 100 0 6.6 93.3 N.A. 13.3 6.6 N.A. 0 0 0 0 N.A. 0 20 13.3 0
P-Site Similarity: 100 20 20 93.3 N.A. 26.6 20 N.A. 0 0 40 0 N.A. 6.6 33.3 20 13.3
Percent
Protein Identity: N.A. 28 N.A. 24.7 30.7 N.A.
Protein Similarity: N.A. 45.2 N.A. 39.9 48.2 N.A.
P-Site Identity: N.A. 0 N.A. 0 0 N.A.
P-Site Similarity: N.A. 13.3 N.A. 13.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 12 18 18 6 0 6 12 0 12 6 24 18 % A
% Cys: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 6 % C
% Asp: 6 0 12 0 0 0 12 12 0 0 18 0 12 12 0 % D
% Glu: 0 12 24 12 0 24 18 12 6 0 6 6 6 6 6 % E
% Phe: 0 0 0 0 12 0 0 0 0 0 0 0 6 0 0 % F
% Gly: 6 6 0 6 0 6 0 12 0 0 12 12 12 0 6 % G
% His: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % H
% Ile: 0 6 0 0 0 0 0 6 0 0 0 12 6 0 6 % I
% Lys: 0 6 6 0 6 0 12 12 12 12 12 6 18 6 6 % K
% Leu: 36 0 0 30 12 6 6 12 12 6 0 18 0 12 12 % L
% Met: 0 0 0 6 6 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 6 6 6 6 0 0 6 0 0 6 0 0 12 0 % N
% Pro: 0 12 6 0 12 6 0 6 12 12 12 6 12 0 0 % P
% Gln: 6 12 12 6 0 0 12 6 0 0 6 0 0 0 6 % Q
% Arg: 0 0 0 0 6 6 6 0 0 0 12 18 0 6 6 % R
% Ser: 12 0 12 6 0 6 6 12 30 30 6 6 6 6 0 % S
% Thr: 12 18 18 12 12 6 6 0 18 18 0 6 18 12 12 % T
% Val: 12 24 6 6 6 6 18 6 6 12 12 0 0 6 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 6 12 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _