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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
9.09
Human Site:
S409
Identified Species:
12.5
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
S409
E
T
A
P
E
D
S
S
P
R
G
T
L
A
S
Chimpanzee
Pan troglodytes
XP_513131
442
49225
K226
K
S
L
F
G
R
K
K
K
K
S
K
N
H
A
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
S409
V
E
T
A
P
E
D
S
S
P
R
G
T
L
A
Dog
Lupus familis
XP_532604
646
71462
S409
E
T
A
P
E
D
S
S
P
R
G
T
L
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
L410
G
D
G
F
E
E
G
L
T
V
A
T
V
V
E
Rat
Rattus norvegicus
Q9R011
615
68782
S378
V
E
T
A
A
E
D
S
S
P
R
G
T
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
K538
P
P
N
M
T
V
V
K
S
G
A
P
A
T
D
Chicken
Gallus gallus
XP_422425
639
71988
E393
P
V
E
T
L
V
E
E
T
S
R
K
S
T
S
Frog
Xenopus laevis
P70032
598
68193
A380
Q
Q
L
T
C
L
N
A
V
K
P
S
E
R
A
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
P390
V
Q
L
A
S
S
G
P
L
D
T
P
A
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
L362
I
E
S
L
Y
Q
Q
L
T
N
L
I
N
G
K
Honey Bee
Apis mellifera
XP_396707
575
66141
S361
Q
T
L
R
E
Q
L
S
A
V
L
K
A
K
P
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
T382
N
D
L
L
A
T
P
T
A
D
I
D
D
A
E
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
P370
T
S
V
V
A
A
K
P
S
E
K
A
D
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
T384
T
N
E
N
V
V
L
T
S
Q
L
D
R
H
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
T225
V
E
M
Y
R
K
I
T
K
G
E
F
K
C
P
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
V430
T
K
Q
K
Y
K
E
V
V
D
I
E
A
Q
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
0
6.6
100
N.A.
13.3
6.6
N.A.
0
6.6
0
0
N.A.
0
20
6.6
0
P-Site Similarity:
100
26.6
20
100
N.A.
26.6
20
N.A.
0
6.6
40
0
N.A.
6.6
26.6
13.3
6.6
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
0
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
6.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
18
18
6
0
6
12
0
12
6
24
18
24
% A
% Cys:
0
0
0
0
6
0
0
0
0
0
0
0
0
6
0
% C
% Asp:
0
12
0
0
0
12
12
0
0
18
0
12
12
0
6
% D
% Glu:
12
24
12
0
24
18
12
6
0
6
6
6
6
6
18
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
6
0
0
0
% F
% Gly:
6
0
6
0
6
0
12
0
0
12
12
12
0
6
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
6
0
0
0
0
0
6
0
0
0
12
6
0
6
0
% I
% Lys:
6
6
0
6
0
12
12
12
12
12
6
18
6
6
6
% K
% Leu:
0
0
30
12
6
6
12
12
6
0
18
0
12
12
0
% L
% Met:
0
0
6
6
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
6
6
6
0
0
6
0
0
6
0
0
12
0
0
% N
% Pro:
12
6
0
12
6
0
6
12
12
12
6
12
0
0
12
% P
% Gln:
12
12
6
0
0
12
6
0
0
6
0
0
0
6
6
% Q
% Arg:
0
0
0
6
6
6
0
0
0
12
18
0
6
6
12
% R
% Ser:
0
12
6
0
6
6
12
30
30
6
6
6
6
0
18
% S
% Thr:
18
18
12
12
6
6
0
18
18
0
6
18
12
12
0
% T
% Val:
24
6
6
6
6
18
6
6
12
12
0
0
6
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _