KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
26.06
Human Site:
S551
Identified Species:
35.83
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
S551
M
K
G
G
D
L
P
S
V
E
E
V
E
V
P
Chimpanzee
Pan troglodytes
XP_513131
442
49225
E350
G
D
L
P
S
V
E
E
V
E
V
P
A
P
P
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
S552
M
K
G
G
D
L
P
S
V
E
E
V
E
V
P
Dog
Lupus familis
XP_532604
646
71462
S551
M
K
G
G
D
L
P
S
V
E
E
V
E
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
S536
M
K
G
G
D
L
P
S
V
E
E
A
E
V
P
Rat
Rattus norvegicus
Q9R011
615
68782
S521
M
K
G
G
D
L
P
S
V
E
E
V
E
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
S700
M
D
G
G
D
L
P
S
V
T
D
V
R
R
P
Chicken
Gallus gallus
XP_422425
639
71988
S544
M
K
G
G
D
L
P
S
I
D
D
L
G
Q
P
Frog
Xenopus laevis
P70032
598
68193
F504
D
E
L
A
R
L
P
F
L
R
T
W
F
R
T
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
R548
M
E
G
G
D
I
N
R
E
D
Q
S
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
Q485
N
V
N
I
E
S
D
Q
I
S
R
M
P
H
L
Honey Bee
Apis mellifera
XP_396707
575
66141
M484
A
V
K
P
C
D
A
M
S
R
I
P
Y
M
H
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
N529
S
N
G
T
V
Q
I
N
F
F
N
D
H
I
K
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
F496
L
P
F
L
Q
S
W
F
R
T
K
S
A
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
Y534
T
H
Y
S
L
T
E
Y
P
K
D
L
Q
K
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
A348
V
S
K
F
E
E
I
A
T
S
S
E
R
F
N
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
R605
S
R
V
S
T
F
G
R
E
E
Y
H
K
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
20
100
93.3
N.A.
93.3
100
N.A.
66.6
60
13.3
26.6
N.A.
0
0
6.6
0
P-Site Similarity:
100
26.6
100
93.3
N.A.
93.3
100
N.A.
73.3
86.6
26.6
53.3
N.A.
20
6.6
20
20
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
0
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
6
0
0
6
6
0
0
0
6
12
0
0
% A
% Cys:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
12
0
0
48
6
6
0
0
12
18
6
0
6
6
% D
% Glu:
0
12
0
0
12
6
12
6
12
42
30
6
30
0
0
% E
% Phe:
0
0
6
6
0
6
0
12
6
6
0
0
6
6
0
% F
% Gly:
6
0
53
48
0
0
6
0
0
0
0
0
6
0
0
% G
% His:
0
6
0
0
0
0
0
0
0
0
0
6
6
6
6
% H
% Ile:
0
0
0
6
0
6
12
0
12
0
6
0
0
12
0
% I
% Lys:
0
36
12
0
0
0
0
0
0
6
6
0
6
6
12
% K
% Leu:
6
0
12
6
6
48
0
0
6
0
0
12
0
0
6
% L
% Met:
48
0
0
0
0
0
0
6
0
0
0
6
0
6
0
% M
% Asn:
6
6
6
0
0
0
6
6
0
0
6
0
0
0
6
% N
% Pro:
0
6
0
12
0
0
48
0
6
0
0
12
6
6
42
% P
% Gln:
0
0
0
0
6
6
0
6
0
0
6
0
6
6
0
% Q
% Arg:
0
6
0
0
6
0
0
12
6
12
6
0
12
12
6
% R
% Ser:
12
6
0
12
6
12
0
42
6
12
6
12
6
6
6
% S
% Thr:
6
0
0
6
6
6
0
0
6
12
6
0
0
0
6
% T
% Val:
6
12
6
0
6
6
0
0
42
0
6
30
0
30
6
% V
% Trp:
0
0
0
0
0
0
6
0
0
0
0
6
0
0
0
% W
% Tyr:
0
0
6
0
0
0
0
6
0
0
6
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _