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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
13.64
Human Site:
S644
Identified Species:
18.75
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
S644
L
R
L
L
R
D
R
S
P
A
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_513131
442
49225
S440
L
R
L
L
R
D
R
S
P
A
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
S645
L
R
L
L
R
D
R
S
P
A
_
_
_
_
_
Dog
Lupus familis
XP_532604
646
71462
C644
L
R
L
L
R
D
R
C
P
A
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
S629
L
R
L
L
R
D
Q
S
P
A
_
_
_
_
_
Rat
Rattus norvegicus
Q9R011
615
68782
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
R792
A
L
N
M
L
L
Q
R
C
N
_
_
_
_
_
Chicken
Gallus gallus
XP_422425
639
71988
A637
L
K
L
L
Q
E
W
A
D
A
_
_
_
_
_
Frog
Xenopus laevis
P70032
598
68193
K595
K
S
A
V
A
H
V
K
A
S
A
_
_
_
_
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
H640
Y
V
V
Q
L
L
Q
H
Y
T
N
A
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
Honey Bee
Apis mellifera
XP_396707
575
66141
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
A625
S
A
A
D
I
Q
P
A
Y
P
S
S
S
R
R
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
L695
L
T
L
I
K
E
G
L
K
Q
K
S
T
I
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
100
100
90
N.A.
90
0
N.A.
0
40
0
0
N.A.
0
0
0
0
P-Site Similarity:
100
100
100
90
N.A.
100
0
N.A.
20
80
18.1
16.6
N.A.
0
0
6.6
0
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
0
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
12
0
6
0
0
12
6
36
6
6
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
6
6
0
0
0
0
0
0
% C
% Asp:
0
0
0
6
0
30
0
0
6
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
6
0
6
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
6
6
0
0
0
0
0
0
0
0
6
0
% I
% Lys:
6
6
0
0
6
0
0
6
6
0
6
0
0
0
0
% K
% Leu:
42
6
42
36
12
12
0
6
0
0
0
0
0
0
0
% L
% Met:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
6
0
0
0
0
0
0
6
6
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
6
0
30
6
0
0
0
0
0
% P
% Gln:
0
0
0
6
6
6
18
0
0
6
0
0
0
0
0
% Q
% Arg:
0
30
0
0
30
0
24
6
0
0
0
0
0
6
6
% R
% Ser:
6
6
0
0
0
0
0
24
0
6
6
12
6
0
0
% S
% Thr:
0
6
0
0
0
0
0
0
0
6
0
0
6
0
0
% T
% Val:
0
6
6
6
0
0
6
0
0
0
0
0
0
0
6
% V
% Trp:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
42
48
53
53
53
% _