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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLK3 All Species: 13.64
Human Site: T194 Identified Species: 18.75
UniProt: Q9H4B4 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H4B4 NP_004064.2 646 71629 T194 K L G N F F I T E N M E L K V
Chimpanzee Pan troglodytes XP_513131 442 49225 H25 A H I W K A R H T L L E P E V
Rhesus Macaque Macaca mulatta XP_001099497 647 71861 T194 K L G N F F I T E N M E L K V
Dog Lupus familis XP_532604 646 71462 T194 K L G N F F I T E N M E L K M
Cat Felis silvestris
Mouse Mus musculus Q60806 631 69994 T195 K L G N F F I T D N M E L K V
Rat Rattus norvegicus Q9R011 615 68782 D172 N M E L K V G D F G L A A R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507288 794 90557 N323 K L G N F F I N E A M E L K V
Chicken Gallus gallus XP_422425 639 71988 N178 K L G N F F I N E N M E L K V
Frog Xenopus laevis P70032 598 68193 N176 K L G N L F L N D E M E V K I
Zebra Danio Brachydanio rerio NP_958465 644 72571 N175 K L G N F F V N E N M E L R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52304 576 66955 H161 L F L N D L L H V K I G D F G
Honey Bee Apis mellifera XP_396707 575 66141 V160 F L S D D L Q V K I G D F G L
Nematode Worm Caenorhab. elegans Q9N2L7 632 72053 D177 E L Q V K I G D F G L A T T C
Sea Urchin Strong. purpuratus XP_784826 587 66895 D168 N M E L K V G D F G L A T K V
Poplar Tree Populus trichocarpa
Maize Zea mays P0C8M8 626 70215 D177 K M E L K I C D F G L A A K L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJ54 439 50149 A24 L L G Q G T F A K V Y H A R N
Baker's Yeast Sacchar. cerevisiae P32562 705 81013 D213 K L G N I F F D S N Y N L K I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.4 98.4 92.2 N.A. 91 89.7 N.A. 44.3 65.7 40.2 58.6 N.A. 36.8 36.6 35.7 40
Protein Similarity: 100 67.9 98.6 94.8 N.A. 93.5 92.4 N.A. 57.8 80.6 58.5 76.9 N.A. 55.8 56.5 55.1 58.9
P-Site Identity: 100 13.3 100 93.3 N.A. 93.3 0 N.A. 86.6 93.3 53.3 73.3 N.A. 6.6 6.6 6.6 13.3
P-Site Similarity: 100 26.6 100 100 N.A. 100 26.6 N.A. 86.6 93.3 80 93.3 N.A. 20 33.3 20 26.6
Percent
Protein Identity: N.A. 28 N.A. 24.7 30.7 N.A.
Protein Similarity: N.A. 45.2 N.A. 39.9 48.2 N.A.
P-Site Identity: N.A. 13.3 N.A. 13.3 53.3 N.A.
P-Site Similarity: N.A. 33.3 N.A. 26.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 0 0 6 0 6 0 6 0 24 18 0 0 % A
% Cys: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 6 % C
% Asp: 0 0 0 6 12 0 0 30 12 0 0 6 6 0 0 % D
% Glu: 6 0 18 0 0 0 0 0 36 6 0 53 0 6 0 % E
% Phe: 6 6 0 0 42 53 12 0 24 0 0 0 6 6 0 % F
% Gly: 0 0 59 0 6 0 18 0 0 24 6 6 0 6 6 % G
% His: 0 6 0 0 0 0 0 12 0 0 0 6 0 0 0 % H
% Ile: 0 0 6 0 6 12 36 0 0 6 6 0 0 0 12 % I
% Lys: 59 0 0 0 30 0 0 0 12 6 0 0 0 59 0 % K
% Leu: 12 71 6 18 6 12 12 0 0 6 30 0 48 0 24 % L
% Met: 0 18 0 0 0 0 0 0 0 0 48 0 0 0 6 % M
% Asn: 12 0 0 59 0 0 0 24 0 42 0 6 0 0 6 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % P
% Gln: 0 0 6 6 0 0 6 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 6 0 0 0 0 0 0 18 0 % R
% Ser: 0 0 6 0 0 0 0 0 6 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 6 0 24 6 0 0 0 12 6 0 % T
% Val: 0 0 0 6 0 12 6 6 6 6 0 0 6 0 42 % V
% Trp: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _