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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLK3 All Species: 7.58
Human Site: T403 Identified Species: 10.42
UniProt: Q9H4B4 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H4B4 NP_004064.2 646 71629 T403 A P V S L V E T A P E D S S P
Chimpanzee Pan troglodytes XP_513131 442 49225 S220 L F A K V T K S L F G R K K K
Rhesus Macaque Macaca mulatta XP_001099497 647 71861 E403 P A P V S L V E T A P E D S S
Dog Lupus familis XP_532604 646 71462 T403 A P L G L A E T A P E D S S P
Cat Felis silvestris
Mouse Mus musculus Q60806 631 69994 D404 G T L A S S G D G F E E G L T
Rat Rattus norvegicus Q9R011 615 68782 E372 L A P V S L V E T A A E D S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507288 794 90557 P532 T D E E I Q P P N M T V V K S
Chicken Gallus gallus XP_422425 639 71988 V387 C S A G S S P V E T L V E E T
Frog Xenopus laevis P70032 598 68193 Q374 Y L S E M L Q Q L T C L N A V
Zebra Danio Brachydanio rerio NP_958465 644 72571 Q384 E A T S P T V Q L A S S G P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52304 576 66955 E356 E D Y R S D I E S L Y Q Q L T
Honey Bee Apis mellifera XP_396707 575 66141 T355 D I R K M L Q T L R E Q L S A
Nematode Worm Caenorhab. elegans Q9N2L7 632 72053 D376 N L L A Q V N D L L A T P T A
Sea Urchin Strong. purpuratus XP_784826 587 66895 S364 S L K V H L T S V V A A K P S
Poplar Tree Populus trichocarpa
Maize Zea mays P0C8M8 626 70215 N378 A T T Q A H T N E N V V L T S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJ54 439 50149 E219 F H E Q N L V E M Y R K I T K
Baker's Yeast Sacchar. cerevisiae P32562 705 81013 K424 S L S P G G T K Q K Y K E V V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.4 98.4 92.2 N.A. 91 89.7 N.A. 44.3 65.7 40.2 58.6 N.A. 36.8 36.6 35.7 40
Protein Similarity: 100 67.9 98.6 94.8 N.A. 93.5 92.4 N.A. 57.8 80.6 58.5 76.9 N.A. 55.8 56.5 55.1 58.9
P-Site Identity: 100 0 6.6 80 N.A. 6.6 6.6 N.A. 0 0 0 6.6 N.A. 0 20 6.6 0
P-Site Similarity: 100 20 20 86.6 N.A. 26.6 20 N.A. 6.6 0 33.3 6.6 N.A. 6.6 40 26.6 20
Percent
Protein Identity: N.A. 28 N.A. 24.7 30.7 N.A.
Protein Similarity: N.A. 45.2 N.A. 39.9 48.2 N.A.
P-Site Identity: N.A. 6.6 N.A. 0 0 N.A.
P-Site Similarity: N.A. 13.3 N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 18 18 12 12 6 6 0 0 12 18 18 6 0 6 12 % A
% Cys: 6 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % C
% Asp: 6 12 0 0 0 6 0 12 0 0 0 12 12 0 0 % D
% Glu: 12 0 12 12 0 0 12 24 12 0 24 18 12 6 0 % E
% Phe: 6 6 0 0 0 0 0 0 0 12 0 0 0 0 0 % F
% Gly: 6 0 0 12 6 6 6 0 6 0 6 0 12 0 0 % G
% His: 0 6 0 0 6 6 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 6 0 0 6 0 6 0 0 0 0 0 6 0 0 % I
% Lys: 0 0 6 12 0 0 6 6 0 6 0 12 12 12 12 % K
% Leu: 12 24 18 0 12 36 0 0 30 12 6 6 12 12 6 % L
% Met: 0 0 0 0 12 0 0 0 6 6 0 0 0 0 0 % M
% Asn: 6 0 0 0 6 0 6 6 6 6 0 0 6 0 0 % N
% Pro: 6 12 12 6 6 0 12 6 0 12 6 0 6 12 12 % P
% Gln: 0 0 0 12 6 6 12 12 6 0 0 12 6 0 0 % Q
% Arg: 0 0 6 6 0 0 0 0 0 6 6 6 0 0 0 % R
% Ser: 12 6 12 12 30 12 0 12 6 0 6 6 12 30 30 % S
% Thr: 6 12 12 0 0 12 18 18 12 12 6 6 0 18 18 % T
% Val: 0 0 6 18 6 12 24 6 6 6 6 18 6 6 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 0 6 0 0 0 0 0 0 6 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _