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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
7.58
Human Site:
T413
Identified Species:
10.42
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
T413
E
D
S
S
P
R
G
T
L
A
S
S
G
D
G
Chimpanzee
Pan troglodytes
XP_513131
442
49225
K230
G
R
K
K
K
K
S
K
N
H
A
Q
E
S
D
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
G413
P
E
D
S
S
P
R
G
T
L
A
S
S
G
D
Dog
Lupus familis
XP_532604
646
71462
T413
E
D
S
S
P
R
G
T
L
A
S
S
G
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
T414
E
E
G
L
T
V
A
T
V
V
E
S
A
L
C
Rat
Rattus norvegicus
Q9R011
615
68782
G382
A
E
D
S
S
P
R
G
T
L
A
S
S
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
P542
T
V
V
K
S
G
A
P
A
T
D
H
K
Q
P
Chicken
Gallus gallus
XP_422425
639
71988
K397
L
V
E
E
T
S
R
K
S
T
S
P
S
V
R
Frog
Xenopus laevis
P70032
598
68193
S384
C
L
N
A
V
K
P
S
E
R
A
L
I
R
Q
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
P394
S
S
G
P
L
D
T
P
A
E
E
E
S
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
I366
Y
Q
Q
L
T
N
L
I
N
G
K
P
R
I
L
Honey Bee
Apis mellifera
XP_396707
575
66141
K365
E
Q
L
S
A
V
L
K
A
K
P
S
R
E
T
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
D386
A
T
P
T
A
D
I
D
D
A
E
A
A
L
D
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
A374
A
A
K
P
S
E
K
A
D
I
R
L
D
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
D388
V
V
L
T
S
Q
L
D
R
H
Q
T
Q
G
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
F229
R
K
I
T
K
G
E
F
K
C
P
N
W
F
P
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
E434
Y
K
E
V
V
D
I
E
A
Q
R
R
L
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
0
13.3
100
N.A.
20
13.3
N.A.
0
6.6
0
0
N.A.
0
20
6.6
0
P-Site Similarity:
100
13.3
26.6
100
N.A.
33.3
26.6
N.A.
0
6.6
33.3
0
N.A.
0
26.6
20
6.6
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
0
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
20
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
6
0
6
12
0
12
6
24
18
24
6
12
0
6
% A
% Cys:
6
0
0
0
0
0
0
0
0
6
0
0
0
0
6
% C
% Asp:
0
12
12
0
0
18
0
12
12
0
6
0
6
12
30
% D
% Glu:
24
18
12
6
0
6
6
6
6
6
18
6
6
12
6
% E
% Phe:
0
0
0
0
0
0
0
6
0
0
0
0
0
6
0
% F
% Gly:
6
0
12
0
0
12
12
12
0
6
0
0
12
18
12
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
6
0
0
0
% H
% Ile:
0
0
6
0
0
0
12
6
0
6
0
0
6
6
0
% I
% Lys:
0
12
12
12
12
12
6
18
6
6
6
0
6
0
6
% K
% Leu:
6
6
12
12
6
0
18
0
12
12
0
12
6
12
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
6
0
0
6
0
0
12
0
0
6
0
6
0
% N
% Pro:
6
0
6
12
12
12
6
12
0
0
12
12
0
0
12
% P
% Gln:
0
12
6
0
0
6
0
0
0
6
6
6
6
6
6
% Q
% Arg:
6
6
0
0
0
12
18
0
6
6
12
6
12
12
6
% R
% Ser:
6
6
12
30
30
6
6
6
6
0
18
36
24
6
0
% S
% Thr:
6
6
0
18
18
0
6
18
12
12
0
6
0
0
6
% T
% Val:
6
18
6
6
12
12
0
0
6
6
0
0
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% W
% Tyr:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _