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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLK3 All Species: 28.18
Human Site: T604 Identified Species: 38.75
UniProt: Q9H4B4 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H4B4 NP_004064.2 646 71629 T604 G W E P L L V T F V A R N R S
Chimpanzee Pan troglodytes XP_513131 442 49225 T400 G W E P L L V T F V A R N R S
Rhesus Macaque Macaca mulatta XP_001099497 647 71861 T605 G W E P L L V T F V A R N R S
Dog Lupus familis XP_532604 646 71462 T604 G W E P L L V T F V A R N R S
Cat Felis silvestris
Mouse Mus musculus Q60806 631 69994 T589 G W E P L L V T F V A R N R S
Rat Rattus norvegicus Q9R011 615 68782 T574 G W E P L L V T F V A R N R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507288 794 90557 L752 S Q S D E Y L L T Y I N E E R
Chicken Gallus gallus XP_422425 639 71988 T597 P D H S C L V T Y I N R E R N
Frog Xenopus laevis P70032 598 68193 T555 D E K R E F R T Y K L S L I Q
Zebra Danio Brachydanio rerio NP_958465 644 72571 L600 K P S D A S Y L V T F I S K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52304 576 66955 Q535 S A I T Y M D Q E K N F R T Y
Honey Bee Apis mellifera XP_396707 575 66141 E534 A V T Y I D T E K N F R T Y R
Nematode Worm Caenorhab. elegans Q9N2L7 632 72053 R585 Y A K C M I Q R L V E E H T K
Sea Urchin Strong. purpuratus XP_784826 587 66895 N546 N F R T F R L N L I E K H G C
Poplar Tree Populus trichocarpa
Maize Zea mays P0C8M8 626 70215 T585 W V K T K N A T L F R L S N K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJ54 439 50149 G398 M V E F K K S G G D T M E Y K
Baker's Yeast Sacchar. cerevisiae P32562 705 81013 Y655 D G G K L V T Y I S P S H E S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.4 98.4 92.2 N.A. 91 89.7 N.A. 44.3 65.7 40.2 58.6 N.A. 36.8 36.6 35.7 40
Protein Similarity: 100 67.9 98.6 94.8 N.A. 93.5 92.4 N.A. 57.8 80.6 58.5 76.9 N.A. 55.8 56.5 55.1 58.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 33.3 6.6 0 N.A. 0 6.6 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 6.6 53.3 20 13.3 N.A. 6.6 13.3 33.3 33.3
Percent
Protein Identity: N.A. 28 N.A. 24.7 30.7 N.A.
Protein Similarity: N.A. 45.2 N.A. 39.9 48.2 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. 20 N.A. 6.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 12 0 0 6 0 6 0 0 0 36 0 0 0 0 % A
% Cys: 0 0 0 6 6 0 0 0 0 0 0 0 0 0 6 % C
% Asp: 12 6 0 12 0 6 6 0 0 6 0 0 0 0 0 % D
% Glu: 0 6 42 0 12 0 0 6 6 0 12 6 18 12 6 % E
% Phe: 0 6 0 6 6 6 0 0 36 6 12 6 0 0 0 % F
% Gly: 36 6 6 0 0 0 0 6 6 0 0 0 0 6 0 % G
% His: 0 0 6 0 0 0 0 0 0 0 0 0 18 0 0 % H
% Ile: 0 0 6 0 6 6 0 0 6 12 6 6 0 6 0 % I
% Lys: 6 0 18 6 12 6 0 0 6 12 0 6 0 6 18 % K
% Leu: 0 0 0 0 42 42 12 12 18 0 6 6 6 0 0 % L
% Met: 6 0 0 0 6 6 0 0 0 0 0 6 0 0 0 % M
% Asn: 6 0 0 0 0 6 0 6 0 6 12 6 36 6 6 % N
% Pro: 6 6 0 36 0 0 0 0 0 0 6 0 0 0 0 % P
% Gln: 0 6 0 0 0 0 6 6 0 0 0 0 0 0 6 % Q
% Arg: 0 0 6 6 0 6 6 6 0 0 6 48 6 42 12 % R
% Ser: 12 0 12 6 0 6 6 0 0 6 0 12 12 0 42 % S
% Thr: 0 0 6 18 0 0 12 53 6 6 6 0 6 12 0 % T
% Val: 0 18 0 0 0 6 42 0 6 42 0 0 0 0 0 % V
% Trp: 6 36 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 0 0 6 6 6 6 6 12 6 0 0 0 12 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _