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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
31.82
Human Site:
Y164
Identified Species:
43.75
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
Y164
L
L
E
P
E
V
R
Y
Y
L
R
Q
I
L
S
Chimpanzee
Pan troglodytes
XP_513131
442
49225
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
Y164
L
L
E
P
E
V
R
Y
Y
L
R
Q
I
L
S
Dog
Lupus familis
XP_532604
646
71462
Y164
L
L
E
P
E
V
R
Y
Y
L
R
Q
I
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
Y165
L
L
E
P
E
V
R
Y
Y
L
R
Q
I
L
S
Rat
Rattus norvegicus
Q9R011
615
68782
H146
L
S
G
L
K
Y
L
H
Q
R
G
I
L
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
Y293
L
T
E
P
E
V
R
Y
Y
L
R
Q
I
V
S
Chicken
Gallus gallus
XP_422425
639
71988
Y148
L
L
E
P
E
V
R
Y
Y
L
K
Q
I
I
S
Frog
Xenopus laevis
P70032
598
68193
Y146
V
T
E
P
E
A
R
Y
Y
L
K
Q
T
I
S
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
Y145
L
T
D
P
E
V
R
Y
Y
L
R
Q
I
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
G135
Y
I
Y
Q
I
I
Q
G
V
K
Y
L
H
D
N
Honey Bee
Apis mellifera
XP_396707
575
66141
V134
M
K
Q
I
L
D
G
V
N
Y
L
H
Q
N
K
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
L150
I
V
E
G
V
L
Y
L
H
N
L
K
I
V
H
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
S142
I
L
A
C
Q
Y
L
S
K
T
K
V
I
H
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
L150
L
I
C
G
L
K
Y
L
H
S
R
R
V
I
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
F183
L
T
E
P
E
V
R
F
F
T
T
Q
I
C
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
0
100
100
N.A.
100
6.6
N.A.
86.6
86.6
60
80
N.A.
0
0
13.3
13.3
P-Site Similarity:
100
0
100
100
N.A.
100
26.6
N.A.
93.3
100
80
93.3
N.A.
26.6
13.3
53.3
33.3
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
13.3
N.A.
0
53.3
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
0
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
0
0
6
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
6
6
0
0
0
0
0
0
0
0
0
6
0
% C
% Asp:
0
0
6
0
0
6
0
0
0
0
0
0
0
6
0
% D
% Glu:
0
0
53
0
53
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
6
6
0
0
0
0
0
0
% F
% Gly:
0
0
6
12
0
0
6
6
0
0
6
0
0
0
6
% G
% His:
0
0
0
0
0
0
0
6
12
0
0
6
6
12
12
% H
% Ile:
12
12
0
6
6
6
0
0
0
0
0
6
59
24
0
% I
% Lys:
0
6
0
0
6
6
0
0
6
6
18
6
0
0
6
% K
% Leu:
59
36
0
6
12
6
12
12
0
48
12
6
6
24
0
% L
% Met:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
6
6
0
0
0
6
6
% N
% Pro:
0
0
0
53
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
6
6
6
0
6
0
6
0
0
53
6
0
0
% Q
% Arg:
0
0
0
0
0
0
53
0
0
6
42
6
0
0
12
% R
% Ser:
0
6
0
0
0
0
0
6
0
6
0
0
0
0
48
% S
% Thr:
0
24
0
0
0
0
0
0
0
12
6
0
6
0
0
% T
% Val:
6
6
0
0
6
48
0
6
6
0
0
6
6
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
6
0
0
12
12
48
48
6
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _