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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
48.48
Human Site:
Y226
Identified Species:
66.67
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
Y226
T
I
C
G
T
P
N
Y
V
A
P
E
V
L
L
Chimpanzee
Pan troglodytes
XP_513131
442
49225
H47
L
S
G
L
K
Y
L
H
Q
R
G
I
L
H
R
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
Y226
T
I
C
G
T
P
N
Y
V
A
P
E
V
L
L
Dog
Lupus familis
XP_532604
646
71462
Y226
T
I
C
G
T
P
N
Y
V
A
P
E
V
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
Y227
T
I
C
G
T
P
N
Y
V
A
P
E
V
L
L
Rat
Rattus norvegicus
Q9R011
615
68782
Y195
T
I
C
G
T
P
N
Y
V
A
P
E
V
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
Y355
T
I
C
G
T
P
N
Y
L
S
P
E
V
L
N
Chicken
Gallus gallus
XP_422425
639
71988
Y210
T
I
C
G
T
P
N
Y
L
A
P
E
V
L
L
Frog
Xenopus laevis
P70032
598
68193
T201
Y
D
G
E
R
K
K
T
L
C
G
T
P
N
Y
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
Y207
T
I
C
G
T
P
N
Y
L
A
P
E
V
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
L183
E
G
E
R
K
K
T
L
C
G
T
P
N
Y
I
Honey Bee
Apis mellifera
XP_396707
575
66141
C182
G
E
R
K
K
T
V
C
G
T
P
N
Y
I
A
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
Y199
T
L
C
G
T
P
N
Y
I
A
P
E
V
L
N
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
Y191
T
L
C
G
T
P
N
Y
I
A
P
E
V
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
Y200
T
V
C
G
T
P
N
Y
I
A
P
E
V
I
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
Q46
A
I
K
V
I
D
K
Q
K
V
A
K
V
G
L
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
Y245
T
I
C
G
T
P
N
Y
I
A
P
E
V
L
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
0
100
93.3
N.A.
100
100
N.A.
80
93.3
0
86.6
N.A.
0
6.6
80
80
P-Site Similarity:
100
13.3
100
93.3
N.A.
100
100
N.A.
93.3
100
6.6
93.3
N.A.
6.6
13.3
93.3
93.3
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
73.3
N.A.
20
86.6
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
26.6
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
0
0
0
0
65
6
0
0
0
6
% A
% Cys:
0
0
71
0
0
0
0
6
6
6
0
0
0
0
0
% C
% Asp:
0
6
0
0
0
6
0
0
0
0
0
0
0
0
0
% D
% Glu:
6
6
6
6
0
0
0
0
0
0
0
71
0
0
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
6
6
12
71
0
0
0
0
6
6
12
0
0
6
0
% G
% His:
0
0
0
0
0
0
0
6
0
0
0
0
0
6
0
% H
% Ile:
0
59
0
0
6
0
0
0
24
0
0
6
0
12
6
% I
% Lys:
0
0
6
6
18
12
12
0
6
0
0
6
0
0
0
% K
% Leu:
6
12
0
6
0
0
6
6
24
0
0
0
6
65
36
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% M
% Asn:
0
0
0
0
0
0
71
0
0
0
0
6
6
6
18
% N
% Pro:
0
0
0
0
0
71
0
0
0
0
77
6
6
0
0
% P
% Gln:
0
0
0
0
0
0
0
6
6
0
0
0
0
0
6
% Q
% Arg:
0
0
6
6
6
0
0
0
0
6
0
0
0
0
6
% R
% Ser:
0
6
0
0
0
0
0
0
0
6
0
0
0
0
6
% S
% Thr:
71
0
0
0
71
6
6
6
0
6
6
6
0
0
0
% T
% Val:
0
6
0
6
0
0
6
0
30
6
0
0
77
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
6
0
71
0
0
0
0
6
6
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _