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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLK3 All Species: 35.45
Human Site: Y538 Identified Species: 48.75
UniProt: Q9H4B4 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H4B4 NP_004064.2 646 71629 Y538 I L R Y F A S Y M E Q H L M K
Chimpanzee Pan troglodytes XP_513131 442 49225 K337 E P L V W V S K W V D Y G G D
Rhesus Macaque Macaca mulatta XP_001099497 647 71861 Y539 I L R Y F T S Y M E Q H L M K
Dog Lupus familis XP_532604 646 71462 Y538 V L R Y F A S Y M E Q R L M K
Cat Felis silvestris
Mouse Mus musculus Q60806 631 69994 Y523 I L R Y F A S Y M E Q H L M K
Rat Rattus norvegicus Q9R011 615 68782 Y508 I L R Y F A S Y M E Q H L M K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507288 794 90557 Y687 V L K Y F S H Y M E E N L M D
Chicken Gallus gallus XP_422425 639 71988 Y531 V L R Y F A S Y M E Q H L M K
Frog Xenopus laevis P70032 598 68193 T491 L L K A G A N T T P R E G D E
Zebra Danio Brachydanio rerio NP_958465 644 72571 Y535 I V D L M A N Y M E Q N L M E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52304 576 66955 V472 R Y M I E H L V K A G A N N V
Honey Bee Apis mellifera XP_396707 575 66141 K471 Y M K E H L M K A G C S F A V
Nematode Worm Caenorhab. elegans Q9N2L7 632 72053 A516 V W F R T K S A I V L H L S N
Sea Urchin Strong. purpuratus XP_784826 587 66895 S483 A A M T P R E S D S M A R L P
Poplar Tree Populus trichocarpa
Maize Zea mays P0C8M8 626 70215 D521 Y I Q R G K N D R Q D T V T H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJ54 439 50149 K335 E S K F T T K K D A K E I V S
Baker's Yeast Sacchar. cerevisiae P32562 705 81013 Y592 V V D F F A K Y M K A N L S R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.4 98.4 92.2 N.A. 91 89.7 N.A. 44.3 65.7 40.2 58.6 N.A. 36.8 36.6 35.7 40
Protein Similarity: 100 67.9 98.6 94.8 N.A. 93.5 92.4 N.A. 57.8 80.6 58.5 76.9 N.A. 55.8 56.5 55.1 58.9
P-Site Identity: 100 6.6 93.3 86.6 N.A. 100 100 N.A. 53.3 93.3 13.3 53.3 N.A. 0 0 20 0
P-Site Similarity: 100 20 93.3 93.3 N.A. 100 100 N.A. 86.6 100 46.6 80 N.A. 0 13.3 33.3 6.6
Percent
Protein Identity: N.A. 28 N.A. 24.7 30.7 N.A.
Protein Similarity: N.A. 45.2 N.A. 39.9 48.2 N.A.
P-Site Identity: N.A. 0 N.A. 0 33.3 N.A.
P-Site Similarity: N.A. 33.3 N.A. 33.3 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 0 6 0 48 0 6 6 12 6 12 0 6 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % C
% Asp: 0 0 12 0 0 0 0 6 12 0 12 0 0 6 12 % D
% Glu: 12 0 0 6 6 0 6 0 0 48 6 12 0 0 12 % E
% Phe: 0 0 6 12 48 0 0 0 0 0 0 0 6 0 0 % F
% Gly: 0 0 0 0 12 0 0 0 0 6 6 0 12 6 0 % G
% His: 0 0 0 0 6 6 6 0 0 0 0 36 0 0 6 % H
% Ile: 30 6 0 6 0 0 0 0 6 0 0 0 6 0 0 % I
% Lys: 0 0 24 0 0 12 12 18 6 6 6 0 0 0 36 % K
% Leu: 6 48 6 6 0 6 6 0 0 0 6 0 59 6 0 % L
% Met: 0 6 12 0 6 0 6 0 53 0 6 0 0 48 0 % M
% Asn: 0 0 0 0 0 0 18 0 0 0 0 18 6 6 6 % N
% Pro: 0 6 0 0 6 0 0 0 0 6 0 0 0 0 6 % P
% Gln: 0 0 6 0 0 0 0 0 0 6 42 0 0 0 0 % Q
% Arg: 6 0 36 12 0 6 0 0 6 0 6 6 6 0 6 % R
% Ser: 0 6 0 0 0 6 48 6 0 6 0 6 0 12 6 % S
% Thr: 0 0 0 6 12 12 0 6 6 0 0 6 0 6 0 % T
% Val: 30 12 0 6 0 6 0 6 0 12 0 0 6 6 12 % V
% Trp: 0 6 0 0 6 0 0 0 6 0 0 0 0 0 0 % W
% Tyr: 12 6 0 42 0 0 0 53 0 0 0 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _