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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
28.18
Human Site:
Y615
Identified Species:
38.75
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
Y615
R
N
R
S
A
C
T
Y
L
A
S
H
L
R
Q
Chimpanzee
Pan troglodytes
XP_513131
442
49225
Y411
R
N
R
S
A
C
T
Y
L
A
S
H
L
R
Q
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
Y616
R
N
R
S
A
C
T
Y
L
A
S
H
L
R
Q
Dog
Lupus familis
XP_532604
646
71462
Y615
R
N
R
S
A
C
T
Y
L
A
S
H
L
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
Y600
R
N
R
S
A
C
T
Y
L
A
S
H
L
R
Q
Rat
Rattus norvegicus
Q9R011
615
68782
Y585
R
N
R
S
A
C
T
Y
L
A
S
H
L
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
T763
N
E
E
R
I
S
T
T
I
R
L
T
T
L
L
Chicken
Gallus gallus
XP_422425
639
71988
Y608
R
E
R
N
S
Y
T
Y
K
L
C
S
I
Q
E
Frog
Xenopus laevis
P70032
598
68193
C566
S
L
I
Q
E
F
G
C
C
K
E
L
A
S
R
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
Y611
I
S
K
E
R
V
S
Y
S
Y
P
L
N
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
T546
F
R
T
Y
R
F
S
T
I
V
E
N
G
V
S
Honey Bee
Apis mellifera
XP_396707
575
66141
I545
R
T
Y
R
F
Q
T
I
Q
E
N
G
C
C
K
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
K596
E
H
T
K
E
E
T
K
H
N
A
P
A
A
N
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
L557
K
H
G
C
T
P
D
L
Y
D
R
I
K
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
V596
L
S
N
K
T
V
Q
V
H
F
T
D
R
T
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
D409
M
E
Y
K
Q
F
C
D
R
E
L
R
P
S
L
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
P666
S
H
E
S
T
T
Y
P
L
V
E
V
L
K
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
26.6
0
6.6
N.A.
0
13.3
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
60
6.6
26.6
N.A.
20
26.6
20
13.3
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
0
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
20
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
36
0
0
0
0
36
6
0
12
6
6
% A
% Cys:
0
0
0
6
0
36
6
6
6
0
6
0
6
6
0
% C
% Asp:
0
0
0
0
0
0
6
6
0
6
0
6
0
0
0
% D
% Glu:
6
18
12
6
12
6
0
0
0
12
18
0
0
0
12
% E
% Phe:
6
0
0
0
6
18
0
0
0
6
0
0
0
0
0
% F
% Gly:
0
0
6
0
0
0
6
0
0
0
0
6
6
0
0
% G
% His:
0
18
0
0
0
0
0
0
12
0
0
36
0
0
0
% H
% Ile:
6
0
6
0
6
0
0
6
12
0
0
6
6
0
0
% I
% Lys:
6
0
6
18
0
0
0
6
6
6
0
0
6
6
6
% K
% Leu:
6
6
0
0
0
0
0
6
42
6
12
12
42
6
18
% L
% Met:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
36
6
6
0
0
0
0
0
6
6
6
6
0
6
% N
% Pro:
0
0
0
0
0
6
0
6
0
0
6
6
6
0
0
% P
% Gln:
0
0
0
6
6
6
6
0
6
0
0
0
0
6
36
% Q
% Arg:
48
6
42
12
12
0
0
0
6
6
6
6
6
36
6
% R
% Ser:
12
12
0
42
6
6
12
0
6
0
36
6
0
12
6
% S
% Thr:
0
6
12
0
18
6
59
12
0
0
6
6
6
6
0
% T
% Val:
0
0
0
0
0
12
0
6
0
12
0
6
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
6
0
6
6
48
6
6
0
0
0
6
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _