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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK3
All Species:
18.79
Human Site:
Y77
Identified Species:
25.83
UniProt:
Q9H4B4
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B4
NP_004064.2
646
71629
Y77
K
G
G
F
A
R
C
Y
E
A
T
D
T
E
T
Chimpanzee
Pan troglodytes
XP_513131
442
49225
Rhesus Macaque
Macaca mulatta
XP_001099497
647
71861
Y77
K
G
G
F
A
R
C
Y
E
A
T
D
T
E
T
Dog
Lupus familis
XP_532604
646
71462
Y77
K
G
G
F
A
R
C
Y
E
A
T
D
T
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60806
631
69994
Y78
K
G
G
F
A
R
C
Y
E
A
T
D
T
E
S
Rat
Rattus norvegicus
Q9R011
615
68782
R73
R
V
A
K
P
H
Q
R
E
K
I
I
N
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507288
794
90557
Y206
K
G
G
F
A
K
C
Y
E
M
T
D
L
T
N
Chicken
Gallus gallus
XP_422425
639
71988
V76
N
K
T
Y
A
V
K
V
I
P
H
S
R
V
A
Frog
Xenopus laevis
P70032
598
68193
F70
D
L
E
S
R
E
V
F
A
G
K
I
V
P
K
Zebra Danio
Brachydanio rerio
NP_958465
644
72571
V73
N
K
M
Y
A
V
K
V
I
P
Q
S
R
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
K63
V
S
K
K
L
M
I
K
H
N
Q
K
E
K
T
Honey Bee
Apis mellifera
XP_396707
575
66141
S62
P
K
S
Q
I
T
K
S
N
Q
R
E
K
M
T
Nematode Worm
Caenorhab. elegans
Q9N2L7
632
72053
Y76
K
A
L
L
I
K
Q
Y
Q
R
D
K
M
A
Q
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
K69
L
L
V
K
P
H
Q
K
D
K
M
T
M
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
K78
S
L
T
K
S
R
A
K
Q
K
L
I
S
E
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJ54
439
50149
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
F97
E
G
G
F
A
R
C
F
Q
I
K
D
D
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
98.4
92.2
N.A.
91
89.7
N.A.
44.3
65.7
40.2
58.6
N.A.
36.8
36.6
35.7
40
Protein Similarity:
100
67.9
98.6
94.8
N.A.
93.5
92.4
N.A.
57.8
80.6
58.5
76.9
N.A.
55.8
56.5
55.1
58.9
P-Site Identity:
100
0
100
93.3
N.A.
93.3
13.3
N.A.
66.6
6.6
0
6.6
N.A.
6.6
6.6
13.3
6.6
P-Site Similarity:
100
0
100
100
N.A.
100
20
N.A.
73.3
13.3
6.6
20
N.A.
13.3
13.3
26.6
13.3
Percent
Protein Identity:
N.A.
28
N.A.
24.7
30.7
N.A.
Protein Similarity:
N.A.
45.2
N.A.
39.9
48.2
N.A.
P-Site Identity:
N.A.
13.3
N.A.
0
46.6
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
0
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
6
0
48
0
6
0
6
24
0
0
0
6
6
% A
% Cys:
0
0
0
0
0
0
36
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
0
0
0
0
0
0
6
0
6
36
6
0
0
% D
% Glu:
6
0
6
0
0
6
0
0
36
0
0
6
6
42
0
% E
% Phe:
0
0
0
36
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
36
36
0
0
0
0
0
0
6
0
0
0
0
6
% G
% His:
0
0
0
0
0
12
0
0
6
0
6
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
6
0
12
6
6
18
0
0
18
% I
% Lys:
36
18
6
24
0
12
18
18
0
18
12
12
6
6
6
% K
% Leu:
6
18
6
6
6
0
0
0
0
0
6
0
6
0
0
% L
% Met:
0
0
6
0
0
6
0
0
0
6
6
0
12
6
0
% M
% Asn:
12
0
0
0
0
0
0
0
6
6
0
0
6
0
6
% N
% Pro:
6
0
0
0
12
0
0
0
0
12
0
0
0
6
0
% P
% Gln:
0
0
0
6
0
0
18
0
18
6
12
0
0
0
6
% Q
% Arg:
6
0
0
0
6
36
0
6
0
6
6
0
12
0
0
% R
% Ser:
6
6
6
6
6
0
0
6
0
0
0
12
6
6
18
% S
% Thr:
0
0
12
0
0
6
0
0
0
0
30
6
24
6
24
% T
% Val:
6
6
6
0
0
12
6
12
0
0
0
0
6
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
36
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _