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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SAV1 All Species: 20.61
Human Site: S115 Identified Species: 37.78
UniProt: Q9H4B6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H4B6 NP_068590.1 383 44634 S115 R E Y G S S Q S F V T E V S F
Chimpanzee Pan troglodytes XP_001156407 384 44672 S116 R E Y G S S Q S F V T E V S F
Rhesus Macaque Macaca mulatta XP_001101888 384 44687 S116 R E Y G S S Q S F V T E V S F
Dog Lupus familis XP_537441 384 44724 S116 R E Y G S S Q S F L T E I N F
Cat Felis silvestris
Mouse Mus musculus Q8VEB2 386 44827 S116 R E C G S S Q S F L T E V N F
Rat Rattus norvegicus A4V8B4 387 45028 S115 V P R E Y G S S Q S F L T E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514664 351 40627 G98 A A E N G D A G S R Y Y Y P E
Chicken Gallus gallus XP_421467 352 40626 G99 V M E N G D A G T R C Y Y Y D
Frog Xenopus laevis NP_001087719 388 44918 S116 P R E Y A S S S Q S F L T D S
Zebra Danio Brachydanio rerio NP_001004560 397 45630 P115 R D Y S P S S P S Y I S D A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCR6 608 68127 P128 P H V R S H P P L P P H Q F R
Honey Bee Apis mellifera XP_624790 382 44223 S115 S T R D G I S S R T A T P M Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794221 372 42467 S115 P T Q Q R G G S P L L P A S A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.4 97.4 N.A. 93.5 93.5 N.A. 80.4 63.9 79.3 65.4 N.A. 28.1 36.8 N.A. 42.3
Protein Similarity: 100 99.7 99.7 99.4 N.A. 96.6 96.9 N.A. 85.3 71.5 87.8 75.8 N.A. 39.3 51.9 N.A. 56.4
P-Site Identity: 100 100 100 80 N.A. 80 6.6 N.A. 0 0 13.3 20 N.A. 6.6 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 6.6 N.A. 0 0 20 33.3 N.A. 6.6 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 8 0 16 0 0 0 8 0 8 8 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 8 0 8 0 16 0 0 0 0 0 0 8 8 8 % D
% Glu: 0 39 24 8 0 0 0 0 0 0 0 39 0 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 39 0 16 0 0 8 39 % F
% Gly: 0 0 0 39 24 16 8 16 0 0 0 0 0 0 0 % G
% His: 0 8 0 0 0 8 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 8 0 8 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 8 24 8 16 0 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 16 0 0 0 0 0 0 0 0 0 16 0 % N
% Pro: 24 8 0 0 8 0 8 16 8 8 8 8 8 8 0 % P
% Gln: 0 0 8 8 0 0 39 0 16 0 0 0 8 0 0 % Q
% Arg: 47 8 16 8 8 0 0 0 8 16 0 0 0 0 8 % R
% Ser: 8 0 0 8 47 54 31 70 16 16 0 8 0 31 16 % S
% Thr: 0 16 0 0 0 0 0 0 8 8 39 8 16 0 0 % T
% Val: 16 0 8 0 0 0 0 0 0 24 0 0 31 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 39 8 8 0 0 0 0 8 8 16 16 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _