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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SAV1 All Species: 15.76
Human Site: S68 Identified Species: 28.89
UniProt: Q9H4B6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H4B6 NP_068590.1 383 44634 S68 S T S G D V V S R N Q S F L R
Chimpanzee Pan troglodytes XP_001156407 384 44672 S69 T S G D G V V S R N Q S F L R
Rhesus Macaque Macaca mulatta XP_001101888 384 44687 S69 T S G D G V V S R N Q S F L R
Dog Lupus familis XP_537441 384 44724 S69 A S G D G I V S R N Q S F L R
Cat Felis silvestris
Mouse Mus musculus Q8VEB2 386 44827 S69 A S G D G V V S R N Q S F L R
Rat Rattus norvegicus A4V8B4 387 45028 V68 S A S G D G V V S R N Q S F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514664 351 40627 H51 T L I P R P P H E V M R R E S
Chicken Gallus gallus XP_421467 352 40626 E52 P V Q R P P H E I M R R E S N
Frog Xenopus laevis NP_001087719 388 44918 V69 T P S G D G A V S R N Q S F L
Zebra Danio Brachydanio rerio NP_001004560 397 45630 T68 P G P G P Y T T G S V G D V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCR6 608 68127 N81 R S S S T S R N T Y S C T D S
Honey Bee Apis mellifera XP_624790 382 44223 F68 Q P S M V Q K F G N T K T T M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794221 372 42467 P68 P A V P Q W E P I G A P V G R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.4 97.4 N.A. 93.5 93.5 N.A. 80.4 63.9 79.3 65.4 N.A. 28.1 36.8 N.A. 42.3
Protein Similarity: 100 99.7 99.7 99.4 N.A. 96.6 96.9 N.A. 85.3 71.5 87.8 75.8 N.A. 39.3 51.9 N.A. 56.4
P-Site Identity: 100 66.6 66.6 60 N.A. 66.6 33.3 N.A. 0 0 20 6.6 N.A. 6.6 13.3 N.A. 6.6
P-Site Similarity: 100 80 80 80 N.A. 80 33.3 N.A. 6.6 6.6 26.6 26.6 N.A. 20 13.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 16 0 0 0 0 8 0 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 31 24 0 0 0 0 0 0 0 8 8 0 % D
% Glu: 0 0 0 0 0 0 8 8 8 0 0 0 8 8 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 39 16 0 % F
% Gly: 0 8 31 31 31 16 0 0 16 8 0 8 0 8 0 % G
% His: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 8 0 0 16 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % K
% Leu: 0 8 0 0 0 0 0 0 0 0 0 0 0 39 16 % L
% Met: 0 0 0 8 0 0 0 0 0 8 8 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 8 0 47 16 0 0 0 8 % N
% Pro: 24 16 8 16 16 16 8 8 0 0 0 8 0 0 0 % P
% Gln: 8 0 8 0 8 8 0 0 0 0 39 16 0 0 0 % Q
% Arg: 8 0 0 8 8 0 8 0 39 16 8 16 8 0 47 % R
% Ser: 16 39 39 8 0 8 0 39 16 8 8 39 16 8 24 % S
% Thr: 31 8 0 0 8 0 8 8 8 0 8 0 16 8 0 % T
% Val: 0 8 8 0 8 31 47 16 0 8 8 0 8 8 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _