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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUBB1
All Species:
56.67
Human Site:
Y398
Identified Species:
89.05
UniProt:
Q9H4B7
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B7
NP_110400.1
451
50327
Y398
R
K
A
F
V
H
W
Y
T
S
E
G
M
D
I
Chimpanzee
Pan troglodytes
Q8WP14
444
49773
Y398
R
K
A
F
L
H
W
Y
T
G
E
G
M
D
E
Rhesus Macaque
Macaca mulatta
XP_001082345
451
50234
Y398
R
K
A
F
V
H
W
Y
T
S
E
G
M
D
I
Dog
Lupus familis
XP_543075
458
50159
Y398
R
R
A
F
V
H
W
Y
T
S
E
G
M
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERD7
450
50400
Y398
R
K
A
F
L
H
W
Y
T
G
E
G
M
D
E
Rat
Rattus norvegicus
Q6P9T8
445
49782
Y398
R
K
A
F
L
H
W
Y
T
G
E
G
M
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511352
452
50925
Y398
R
K
A
F
I
H
W
Y
T
G
E
G
M
D
I
Chicken
Gallus gallus
P09207
446
50135
Y398
R
K
A
F
L
H
W
Y
T
G
E
G
M
D
E
Frog
Xenopus laevis
P13602
443
49705
Y398
R
K
A
F
L
H
W
Y
T
G
E
G
M
D
E
Zebra Danio
Brachydanio rerio
XP_686874
466
52560
Y398
R
K
A
F
L
H
W
Y
T
G
E
G
M
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24560
447
50129
Y398
R
K
A
F
L
H
W
Y
T
G
E
G
M
D
E
Honey Bee
Apis mellifera
XP_392313
447
50157
Y398
R
K
A
F
L
H
W
Y
T
G
E
G
M
D
E
Nematode Worm
Caenorhab. elegans
P41937
444
49782
Y398
R
K
A
F
L
H
W
Y
T
G
E
G
M
D
E
Sea Urchin
Strong. purpuratus
XP_791790
447
50098
Y398
R
K
A
F
L
H
W
Y
T
G
E
G
M
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P18025
446
49944
Y398
R
K
A
F
L
H
W
Y
T
G
E
G
M
D
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.6
98.6
81
N.A.
77.8
78
N.A.
87.6
83.5
77.8
76.1
N.A.
78
77.8
76.7
78.2
Protein Similarity:
100
86.9
99.3
91.4
N.A.
89.1
88.2
N.A.
94.2
91.8
88.2
87.7
N.A.
88.9
88.9
88
88.4
P-Site Identity:
100
80
100
86.6
N.A.
80
80
N.A.
86.6
80
80
80
N.A.
80
80
80
80
P-Site Similarity:
100
86.6
100
100
N.A.
86.6
86.6
N.A.
93.3
86.6
86.6
86.6
N.A.
86.6
86.6
86.6
86.6
Percent
Protein Identity:
N.A.
73.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
85.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
80
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
74
% E
% Phe:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
80
0
100
0
0
0
% G
% His:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
20
% I
% Lys:
0
94
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
74
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
100
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% T
% Val:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _