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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPEP3
All Species:
18.18
Human Site:
S249
Identified Species:
44.44
UniProt:
Q9H4B8
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4B8
NP_001123230.1
488
53687
S249
T
N
V
S
G
L
T
S
F
G
E
K
V
V
E
Chimpanzee
Pan troglodytes
XP_523398
512
56301
S274
T
N
V
S
G
L
T
S
F
G
E
K
V
V
E
Rhesus Macaque
Macaca mulatta
XP_001096561
513
56703
S274
T
N
V
S
G
L
T
S
F
G
E
K
V
V
E
Dog
Lupus familis
XP_853810
465
51664
L241
R
L
G
M
M
V
D
L
S
H
V
S
D
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DA79
493
54229
S246
T
N
I
S
G
L
T
S
F
G
E
K
V
V
E
Rat
Rattus norvegicus
Q5U2X4
488
53352
S246
T
N
I
S
G
L
T
S
F
G
E
K
V
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511283
510
56609
P292
P
E
S
N
G
L
S
P
F
G
Q
R
V
V
K
Chicken
Gallus gallus
XP_414081
403
45181
M195
K
E
M
N
R
L
G
M
L
I
D
L
S
H
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070805
413
46950
M205
G
K
Q
V
V
W
E
M
N
R
I
G
M
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393772
429
47457
D221
T
V
E
D
E
D
E
D
G
G
G
L
T
A
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
89.6
66.3
N.A.
72.2
73.3
N.A.
38.8
45.7
N.A.
38.7
N.A.
N.A.
39.5
N.A.
N.A.
Protein Similarity:
100
93.7
91.4
74.8
N.A.
82.1
84.4
N.A.
56
60.8
N.A.
55.1
N.A.
N.A.
54.5
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
93.3
93.3
N.A.
40
6.6
N.A.
0
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
73.3
26.6
N.A.
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
10
10
0
0
10
0
10
0
0
% D
% Glu:
0
20
10
0
10
0
20
0
0
0
50
0
0
0
50
% E
% Phe:
0
0
0
0
0
0
0
0
60
0
0
0
0
0
10
% F
% Gly:
10
0
10
0
60
0
10
0
10
70
10
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% H
% Ile:
0
0
20
0
0
0
0
0
0
10
10
0
0
0
10
% I
% Lys:
10
10
0
0
0
0
0
0
0
0
0
50
0
0
10
% K
% Leu:
0
10
0
0
0
70
0
10
10
0
0
20
0
10
0
% L
% Met:
0
0
10
10
10
0
0
20
0
0
0
0
10
0
0
% M
% Asn:
0
50
0
20
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
10
0
0
0
10
0
0
0
0
10
0
10
0
0
0
% R
% Ser:
0
0
10
50
0
0
10
50
10
0
0
10
10
0
0
% S
% Thr:
60
0
0
0
0
0
50
0
0
0
0
0
10
10
10
% T
% Val:
0
10
30
10
10
10
0
0
0
0
10
0
60
60
10
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _