KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHA4
All Species:
8.48
Human Site:
S527
Identified Species:
31.11
UniProt:
Q9H4M7
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H4M7
NP_001154826.1
779
85401
S527
E
R
E
S
L
P
E
S
L
E
L
S
S
P
R
Chimpanzee
Pan troglodytes
XP_512804
472
51801
G242
R
P
P
T
P
R
R
G
P
P
S
E
A
G
G
Rhesus Macaque
Macaca mulatta
XP_001112238
641
70289
R411
Q
Q
L
G
Q
A
T
R
E
A
G
A
P
G
R
Dog
Lupus familis
XP_541508
778
85135
S527
E
R
E
S
L
P
E
S
L
E
L
S
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC98
588
64820
D358
L
L
P
G
P
P
V
D
S
A
L
H
Q
S
L
Rat
Rattus norvegicus
P60669
779
85624
S530
E
R
E
S
L
S
E
S
L
E
L
S
S
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421001
1256
142432
E771
Q
K
D
L
W
R
I
E
D
V
T
A
G
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.8
66.7
87
N.A.
63.5
80.2
N.A.
N.A.
25.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
60.2
70
90.2
N.A.
67.9
86.2
N.A.
N.A.
38
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
6.6
93.3
N.A.
13.3
86.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
26.6
93.3
N.A.
13.3
93.3
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
15
0
0
0
29
0
29
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
0
0
0
15
15
0
0
0
0
0
0
% D
% Glu:
43
0
43
0
0
0
43
15
15
43
0
15
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
29
0
0
0
15
0
0
15
0
15
29
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% H
% Ile:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% I
% Lys:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
15
15
15
15
43
0
0
0
43
0
58
0
0
15
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
15
29
0
29
43
0
0
15
15
0
0
15
29
0
% P
% Gln:
29
15
0
0
15
0
0
0
0
0
0
0
15
0
15
% Q
% Arg:
15
43
0
0
0
29
15
15
0
0
0
0
0
0
43
% R
% Ser:
0
0
0
43
0
15
0
43
15
0
15
43
43
29
15
% S
% Thr:
0
0
0
15
0
0
15
0
0
0
15
0
0
0
0
% T
% Val:
0
0
0
0
0
0
15
0
0
15
0
0
0
0
0
% V
% Trp:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _