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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF41 All Species: 9.09
Human Site: S104 Identified Species: 20
UniProt: Q9H4P4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H4P4 NP_005776.1 317 35905 S104 D N L M S H L S D C E H N P K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta B6CJY5 522 59446 Q263 N H L A R H L Q E N T Q S H M
Dog Lupus familis XP_856914 297 33583 C96 N P K R P V T C E Q G C G L E
Cat Felis silvestris
Mouse Mus musculus Q8BH75 317 35873 S104 D N L M S H L S D C E H N P K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516965 213 24049 M50 L R Q R Q F G M E W G P P S A
Chicken Gallus gallus XP_424113 171 19645 F8 A P H C E H A F C N A C I T Q
Frog Xenopus laevis Q5FWL3 317 35893 S104 D N L M S H L S D C E H N P K
Zebra Danio Brachydanio rerio Q7ZW16 318 36109 K104 D Q L Q S H L K D C E H N P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648816 315 36074 D104 D A Y N S H L D E C I H N P K
Honey Bee Apis mellifera XP_395055 315 36439 E104 D S L V S H L E Q C E Y N P K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780194 319 36626 Q104 D S L Q Q H L Q E C E H N P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 20.5 93.3 N.A. 99.6 N.A. N.A. 59.9 53 94.9 90.2 N.A. 57 57.4 N.A. 63.3
Protein Similarity: 100 N.A. 33.1 93.6 N.A. 100 N.A. N.A. 62.7 53.6 97.7 96.8 N.A. 78.2 79.1 N.A. 81.1
P-Site Identity: 100 N.A. 20 0 N.A. 100 N.A. N.A. 0 6.6 100 80 N.A. 60 66.6 N.A. 66.6
P-Site Similarity: 100 N.A. 46.6 20 N.A. 100 N.A. N.A. 6.6 13.3 100 80 N.A. 66.6 86.6 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 10 0 0 10 0 0 0 10 0 0 0 10 % A
% Cys: 0 0 0 10 0 0 0 10 10 64 0 19 0 0 0 % C
% Asp: 64 0 0 0 0 0 0 10 37 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 10 0 0 10 46 0 55 0 0 0 10 % E
% Phe: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 0 19 0 10 0 0 % G
% His: 0 10 10 0 0 82 0 0 0 0 0 55 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % I
% Lys: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 64 % K
% Leu: 10 0 64 0 0 0 73 0 0 0 0 0 0 10 0 % L
% Met: 0 0 0 28 0 0 0 10 0 0 0 0 0 0 10 % M
% Asn: 19 28 0 10 0 0 0 0 0 19 0 0 64 0 0 % N
% Pro: 0 19 0 0 10 0 0 0 0 0 0 10 10 64 0 % P
% Gln: 0 10 10 19 19 0 0 19 10 10 0 10 0 0 10 % Q
% Arg: 0 10 0 19 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 19 0 0 55 0 0 28 0 0 0 0 10 10 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 10 0 0 10 0 % T
% Val: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _