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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRDM12 All Species: 17.27
Human Site: S73 Identified Species: 38
UniProt: Q9H4Q4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H4Q4 NP_067632.2 367 40403 S73 E V L A Q S F S G E V Q K L S
Chimpanzee Pan troglodytes XP_528445 366 40314 S73 E V L A Q S F S G E V Q K L S
Rhesus Macaque Macaca mulatta XP_001082029 571 64054 P239 S S G S D S L P Q T V D K D S
Dog Lupus familis XP_850786 571 62766 V224 P H P T P V V V T E V Q K L S
Cat Felis silvestris
Mouse Mus musculus Q3UZD5 596 64484 P234 S S A A A A A P P P E L P E W
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507301 260 29382 H25 E R V G S T V H S R F L G F H
Chicken Gallus gallus Q90625 706 76801 P157 K I P K A A Q P K S E S K E N
Frog Xenopus laevis NP_001079854 355 39757 S73 E V L A Q S F S G E V Q K L S
Zebra Danio Brachydanio rerio NP_001007458 366 40835 S72 E V L A Q S F S G E V Q K L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q966L8 279 31577 S44 D S T S S M P S S G T T Q Q A
Sea Urchin Strong. purpuratus XP_790201 330 37558 T73 V V L G V F S T D W I K E G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 23.2 53.2 N.A. 22.8 N.A. N.A. 61 20.6 86 82.2 N.A. N.A. N.A. 21.5 45.2
Protein Similarity: 100 99.7 36.7 56.9 N.A. 35.5 N.A. N.A. 65.1 30.5 90.4 87.4 N.A. N.A. N.A. 35.9 64
P-Site Identity: 100 100 26.6 40 N.A. 6.6 N.A. N.A. 6.6 6.6 100 100 N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: 100 100 33.3 40 N.A. 13.3 N.A. N.A. 20 33.3 100 100 N.A. N.A. N.A. 33.3 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 46 19 19 10 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 10 0 0 0 10 0 0 10 0 10 0 % D
% Glu: 46 0 0 0 0 0 0 0 0 46 19 0 10 19 0 % E
% Phe: 0 0 0 0 0 10 37 0 0 0 10 0 0 10 0 % F
% Gly: 0 0 10 19 0 0 0 0 37 10 0 0 10 10 0 % G
% His: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 10 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 10 0 0 10 0 0 0 0 10 0 0 10 64 0 0 % K
% Leu: 0 0 46 0 0 0 10 0 0 0 0 19 0 46 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 10 0 19 0 10 0 10 28 10 10 0 0 10 0 0 % P
% Gln: 0 0 0 0 37 0 10 0 10 0 0 46 10 10 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 19 28 0 19 19 46 10 46 19 10 0 10 0 0 55 % S
% Thr: 0 0 10 10 0 10 0 10 10 10 10 10 0 0 10 % T
% Val: 10 46 10 0 10 10 19 10 0 0 55 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _