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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCIF1 All Species: 40.3
Human Site: S253 Identified Species: 80.61
UniProt: Q9H4Z3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H4Z3 NP_071387.1 704 80670 S253 G S D P L L P S N C E P V V S
Chimpanzee Pan troglodytes XP_001160566 685 78201 V243 W M L E R K V V D K G S D P L
Rhesus Macaque Macaca mulatta XP_001105319 700 79571 S253 G S D P L L P S N C E P V V S
Dog Lupus familis XP_534442 702 80548 S253 G S D P L L P S N C E P V V S
Cat Felis silvestris
Mouse Mus musculus P59114 706 80486 S252 G C D P L L P S N C E P V V S
Rat Rattus norvegicus NP_001102075 704 80562 S252 G C D P L L P S N C E P V V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234172 707 80672 S253 G T D P L L P S D C E P V V S
Frog Xenopus laevis NP_001089204 691 78730 S245 G P D P L L P S D C D P A V S
Zebra Danio Brachydanio rerio XP_688220 716 80676 S252 G L D P L L P S E C D P V I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649254 920 100272 S317 G C D P L L P S S C M P E I S
Honey Bee Apis mellifera XP_624144 729 82623 S265 G S D P L L P S Q C F P E I S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786170 1094 122452 S323 G K D P M L P S Q C P D P V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.4 90 98 N.A. 95 96 N.A. N.A. 86.6 70.5 67.1 N.A. 33.9 43.7 N.A. 31.3
Protein Similarity: 100 91.4 92 98.8 N.A. 97.5 98.1 N.A. N.A. 92.3 84.3 82.1 N.A. 47.3 58.8 N.A. 42.7
P-Site Identity: 100 0 100 100 N.A. 93.3 93.3 N.A. N.A. 86.6 73.3 73.3 N.A. 66.6 73.3 N.A. 60
P-Site Similarity: 100 6.6 100 100 N.A. 93.3 93.3 N.A. N.A. 100 86.6 86.6 N.A. 80 80 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % A
% Cys: 0 25 0 0 0 0 0 0 0 92 0 0 0 0 0 % C
% Asp: 0 0 92 0 0 0 0 0 25 0 17 9 9 0 0 % D
% Glu: 0 0 0 9 0 0 0 0 9 0 50 0 17 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 92 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 % I
% Lys: 0 9 0 0 0 9 0 0 0 9 0 0 0 0 0 % K
% Leu: 0 9 9 0 84 92 0 0 0 0 0 0 0 0 9 % L
% Met: 0 9 0 0 9 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 42 0 0 0 0 0 0 % N
% Pro: 0 9 0 92 0 0 92 0 0 0 9 84 9 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 34 0 0 0 0 0 92 9 0 0 9 0 0 92 % S
% Thr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 9 9 0 0 0 0 59 67 0 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _