KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESF1
All Species:
4.55
Human Site:
S190
Identified Species:
9.09
UniProt:
Q9H501
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H501
NP_057733.2
851
98796
S190
E
K
Q
R
T
L
D
S
G
T
S
E
I
V
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083468
849
98477
S191
E
K
R
R
T
L
D
S
G
T
S
E
I
V
K
Dog
Lupus familis
XP_534341
849
98634
D190
K
G
K
L
S
T
G
D
L
G
L
S
E
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1V3
845
98030
G185
S
V
E
A
L
P
K
G
K
L
R
T
K
D
S
Rat
Rattus norvegicus
Q76MT4
842
97516
P190
G
K
L
R
T
K
D
P
S
T
S
A
M
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514209
839
97846
N190
G
I
K
K
Q
K
D
N
F
I
A
V
S
P
K
Chicken
Gallus gallus
NP_001026690
838
97135
C171
Q
K
N
K
D
L
L
C
D
R
E
K
E
E
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956039
757
88784
D166
S
G
V
E
E
D
D
D
D
D
D
D
D
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569906
771
88512
L185
Y
A
R
G
E
G
R
L
Y
T
D
S
S
S
D
Honey Bee
Apis mellifera
XP_624350
533
62517
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781121
795
92011
E186
K
G
K
R
R
D
V
E
P
D
S
D
S
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06344
628
72391
E70
A
Q
N
N
R
E
L
E
D
F
D
K
Y
F
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.5
84.6
N.A.
81.1
80
N.A.
69.2
60.9
N.A.
52.6
N.A.
34
26.5
N.A.
41.3
Protein Similarity:
100
N.A.
96.9
91.4
N.A.
90.1
89.6
N.A.
81.7
76.6
N.A.
68
N.A.
54.4
44.7
N.A.
62.2
P-Site Identity:
100
N.A.
93.3
0
N.A.
0
53.3
N.A.
13.3
13.3
N.A.
6.6
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
N.A.
100
26.6
N.A.
6.6
60
N.A.
40
33.3
N.A.
20
N.A.
13.3
0
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
0
0
0
0
0
0
9
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
17
42
17
25
17
25
17
9
25
9
% D
% Glu:
17
0
9
9
17
9
0
17
0
0
9
17
17
9
17
% E
% Phe:
0
0
0
0
0
0
0
0
9
9
0
0
0
9
0
% F
% Gly:
17
25
0
9
0
9
9
9
17
9
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
9
0
0
17
9
0
% I
% Lys:
17
34
25
17
0
17
9
0
9
0
0
17
9
0
34
% K
% Leu:
0
0
9
9
9
25
17
9
9
9
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
17
9
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
9
9
0
0
0
0
9
0
% P
% Gln:
9
9
9
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
17
34
17
0
9
0
0
9
9
0
0
0
0
% R
% Ser:
17
0
0
0
9
0
0
17
9
0
34
17
25
9
17
% S
% Thr:
0
0
0
0
25
9
0
0
0
34
0
9
0
0
0
% T
% Val:
0
9
9
0
0
0
9
0
0
0
0
9
0
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _