KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESF1
All Species:
6.97
Human Site:
S251
Identified Species:
13.94
UniProt:
Q9H501
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H501
NP_057733.2
851
98796
S251
E
S
V
S
E
I
G
S
D
E
E
S
E
N
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083468
849
98477
E252
E
S
V
S
G
S
D
E
E
S
E
S
E
I
T
Dog
Lupus familis
XP_534341
849
98634
D251
S
E
S
A
S
E
I
D
D
E
E
S
E
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1V3
845
98030
S246
D
S
A
S
E
L
G
S
D
E
E
S
E
D
E
Rat
Rattus norvegicus
Q76MT4
842
97516
S251
E
S
E
G
E
I
T
S
D
D
R
A
S
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514209
839
97846
N251
S
T
E
E
D
S
E
N
D
N
E
T
E
E
E
Chicken
Gallus gallus
NP_001026690
838
97135
I232
D
S
G
A
E
S
D
I
S
E
S
Q
V
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956039
757
88784
P227
G
E
M
W
K
D
A
P
R
S
D
D
T
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569906
771
88512
L246
A
E
D
L
M
V
M
L
S
S
F
L
P
P
G
Honey Bee
Apis mellifera
XP_624350
533
62517
E36
T
D
S
S
S
D
E
E
S
F
Q
T
S
D
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781121
795
92011
C247
G
P
V
M
D
E
I
C
H
N
W
G
E
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06344
628
72391
N131
E
V
E
S
E
E
E
N
E
V
E
I
E
N
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.5
84.6
N.A.
81.1
80
N.A.
69.2
60.9
N.A.
52.6
N.A.
34
26.5
N.A.
41.3
Protein Similarity:
100
N.A.
96.9
91.4
N.A.
90.1
89.6
N.A.
81.7
76.6
N.A.
68
N.A.
54.4
44.7
N.A.
62.2
P-Site Identity:
100
N.A.
46.6
33.3
N.A.
73.3
40
N.A.
26.6
26.6
N.A.
0
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
N.A.
53.3
46.6
N.A.
93.3
60
N.A.
53.3
40
N.A.
26.6
N.A.
6.6
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
17
0
0
9
0
0
0
0
9
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
17
9
9
0
17
17
17
9
42
9
9
9
0
25
17
% D
% Glu:
34
25
25
9
42
25
25
17
17
34
50
0
59
17
42
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% F
% Gly:
17
0
9
9
9
0
17
0
0
0
0
9
0
0
17
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
17
17
9
0
0
0
9
0
9
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
0
9
0
9
0
0
0
9
0
9
0
% L
% Met:
0
0
9
9
9
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
17
0
17
0
0
0
17
0
% N
% Pro:
0
9
0
0
0
0
0
9
0
0
0
0
9
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
9
% R
% Ser:
17
42
17
42
17
25
0
25
25
25
9
34
17
9
0
% S
% Thr:
9
9
0
0
0
0
9
0
0
0
0
17
9
0
9
% T
% Val:
0
9
25
0
0
9
0
0
0
9
0
0
9
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _