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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESF1
All Species:
15.15
Human Site:
S296
Identified Species:
30.3
UniProt:
Q9H501
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H501
NP_057733.2
851
98796
S296
D
S
E
D
D
D
K
S
D
S
G
P
D
L
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083468
849
98477
S294
D
S
E
D
D
D
E
S
D
S
G
P
D
L
A
Dog
Lupus familis
XP_534341
849
98634
S294
D
N
D
D
E
S
D
S
G
P
D
L
A
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1V3
845
98030
S290
E
E
E
E
E
D
E
S
D
S
G
P
D
L
A
Rat
Rattus norvegicus
Q76MT4
842
97516
D293
D
E
S
D
S
G
P
D
L
A
R
G
K
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514209
839
97846
V295
L
A
R
G
R
G
N
V
E
T
S
S
E
D
E
Chicken
Gallus gallus
NP_001026690
838
97135
S288
D
S
E
E
D
E
E
S
D
I
E
P
D
L
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956039
757
88784
T269
G
G
V
V
L
S
V
T
V
Y
P
S
E
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569906
771
88512
P288
E
L
V
E
R
V
E
P
E
D
D
S
D
E
E
Honey Bee
Apis mellifera
XP_624350
533
62517
R78
N
M
D
W
D
R
I
R
A
V
D
L
M
V
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781121
795
92011
P291
V
L
L
N
S
F
K
P
S
G
G
V
L
H
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06344
628
72391
P173
I
T
F
S
S
F
V
P
K
G
G
K
I
E
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.5
84.6
N.A.
81.1
80
N.A.
69.2
60.9
N.A.
52.6
N.A.
34
26.5
N.A.
41.3
Protein Similarity:
100
N.A.
96.9
91.4
N.A.
90.1
89.6
N.A.
81.7
76.6
N.A.
68
N.A.
54.4
44.7
N.A.
62.2
P-Site Identity:
100
N.A.
93.3
20
N.A.
66.6
13.3
N.A.
0
66.6
N.A.
0
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
N.A.
100
40
N.A.
93.3
20
N.A.
26.6
86.6
N.A.
13.3
N.A.
33.3
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
9
9
0
0
9
0
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
42
0
17
34
34
25
9
9
34
9
25
0
42
9
0
% D
% Glu:
17
17
34
25
17
9
34
0
17
0
9
0
17
17
17
% E
% Phe:
0
0
9
0
0
17
0
0
0
0
0
0
0
9
0
% F
% Gly:
9
9
0
9
0
17
0
0
9
17
42
9
0
9
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
9
0
0
0
0
0
9
0
0
9
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
17
0
9
0
0
9
9
0
0
% K
% Leu:
9
17
9
0
9
0
0
0
9
0
0
17
9
34
9
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
9
9
0
9
0
0
9
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
9
25
0
9
9
34
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
17
9
0
9
0
0
9
0
0
9
9
% R
% Ser:
0
25
9
9
25
17
0
42
9
25
9
25
0
0
9
% S
% Thr:
0
9
0
0
0
0
0
9
0
9
0
0
0
0
0
% T
% Val:
9
0
17
9
0
9
17
9
9
9
0
9
0
9
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _