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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL31
All Species:
27.58
Human Site:
S625
Identified Species:
55.15
UniProt:
Q9H511
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H511
NP_001003760.2
634
70246
S625
V
T
R
E
S
R
A
S
S
V
S
S
V
P
V
Chimpanzee
Pan troglodytes
XP_527419
634
70228
S625
V
T
R
E
S
R
A
S
S
V
S
S
V
P
V
Rhesus Macaque
Macaca mulatta
XP_001109056
634
70160
S625
V
T
R
E
S
R
A
S
S
V
S
S
V
P
V
Dog
Lupus familis
XP_538967
634
69490
S625
A
P
R
E
S
R
A
S
S
V
S
S
V
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWA5
634
70163
S625
V
S
R
E
S
R
A
S
S
V
S
S
V
P
V
Rat
Rattus norvegicus
Q66HD2
613
69917
N604
L
E
E
K
K
K
K
N
K
D
K
R
Q
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511063
635
70424
S626
V
A
R
E
S
R
A
S
S
V
S
S
V
P
V
Chicken
Gallus gallus
Q5ZLD3
629
70952
S621
E
D
N
T
G
S
P
S
R
E
S
P
L
S
A
Frog
Xenopus laevis
NP_001086711
635
71326
S627
E
D
N
S
C
S
P
S
R
E
S
P
L
S
A
Zebra Danio
Brachydanio rerio
Q6Q7X9
635
70787
S626
K
T
R
E
S
R
A
S
S
V
S
S
A
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
W613
P
Q
T
E
N
Y
M
W
C
E
N
S
F
K
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789242
643
73217
P608
S
F
F
N
A
S
P
P
N
G
D
S
L
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
99
92.7
N.A.
91.9
30.9
N.A.
86.1
33.2
32.5
75.5
N.A.
26.3
N.A.
N.A.
34.2
Protein Similarity:
100
99.6
99.6
95.9
N.A.
96.6
50
N.A.
94.3
54.8
54.6
88.9
N.A.
45.9
N.A.
N.A.
56.4
P-Site Identity:
100
100
100
86.6
N.A.
93.3
0
N.A.
93.3
13.3
13.3
86.6
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
100
26.6
N.A.
93.3
20
20
86.6
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
9
0
59
0
0
0
0
0
9
0
17
% A
% Cys:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
17
0
0
0
0
0
0
0
9
9
0
0
9
0
% D
% Glu:
17
9
9
67
0
0
0
0
0
25
0
0
0
0
0
% E
% Phe:
0
9
9
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
9
9
9
9
0
9
0
9
0
0
9
0
% K
% Leu:
9
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
9
9
0
0
9
9
0
9
0
0
0
0
% N
% Pro:
9
9
0
0
0
0
25
9
0
0
0
17
0
59
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
9
% Q
% Arg:
0
0
59
0
0
59
0
0
17
0
0
9
0
0
9
% R
% Ser:
9
9
0
9
59
25
0
75
59
0
75
75
0
25
0
% S
% Thr:
0
34
9
9
0
0
0
0
0
0
0
0
0
0
9
% T
% Val:
42
0
0
0
0
0
0
0
0
59
0
0
50
0
59
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _