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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL31
All Species:
23.64
Human Site:
Y422
Identified Species:
47.27
UniProt:
Q9H511
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H511
NP_001003760.2
634
70246
Y422
S
V
F
N
G
L
V
Y
A
A
G
G
R
N
A
Chimpanzee
Pan troglodytes
XP_527419
634
70228
Y422
S
V
F
N
G
L
L
Y
A
A
G
G
R
N
A
Rhesus Macaque
Macaca mulatta
XP_001109056
634
70160
Y422
S
V
F
N
G
L
L
Y
A
A
G
G
R
N
A
Dog
Lupus familis
XP_538967
634
69490
Y422
S
V
C
D
G
L
L
Y
A
A
G
G
R
N
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWA5
634
70163
Y422
S
V
F
N
G
L
L
Y
A
V
G
G
R
N
S
Rat
Rattus norvegicus
Q66HD2
613
69917
G401
E
D
M
L
V
A
V
G
G
R
N
E
N
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511063
635
70424
F423
N
V
L
H
G
L
L
F
A
V
G
G
R
N
A
Chicken
Gallus gallus
Q5ZLD3
629
70952
Y418
S
A
L
K
G
H
L
Y
A
V
G
G
R
N
A
Frog
Xenopus laevis
NP_001086711
635
71326
Y424
S
A
L
K
G
H
L
Y
A
V
G
G
R
N
A
Zebra Danio
Brachydanio rerio
Q6Q7X9
635
70787
F423
N
T
F
N
G
L
L
F
A
V
G
G
R
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
V410
T
T
S
C
R
T
S
V
G
V
A
V
L
D
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789242
643
73217
V405
A
G
L
G
S
S
L
V
A
V
G
G
K
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
99
92.7
N.A.
91.9
30.9
N.A.
86.1
33.2
32.5
75.5
N.A.
26.3
N.A.
N.A.
34.2
Protein Similarity:
100
99.6
99.6
95.9
N.A.
96.6
50
N.A.
94.3
54.8
54.6
88.9
N.A.
45.9
N.A.
N.A.
56.4
P-Site Identity:
100
93.3
93.3
80
N.A.
80
13.3
N.A.
60
60
60
60
N.A.
0
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
86.6
66.6
66.6
86.6
N.A.
13.3
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
0
0
0
9
0
0
84
34
9
0
0
0
67
% A
% Cys:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
0
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% E
% Phe:
0
0
42
0
0
0
0
17
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
9
75
0
0
9
17
0
84
84
0
9
9
% G
% His:
0
0
0
9
0
17
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
17
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
0
0
34
9
0
59
75
0
0
0
0
0
9
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
0
42
0
0
0
0
0
0
9
0
9
84
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
9
0
0
75
0
0
% R
% Ser:
59
0
9
0
9
9
9
0
0
0
0
0
0
0
17
% S
% Thr:
9
17
0
0
0
9
0
0
0
0
0
0
0
0
0
% T
% Val:
0
50
0
0
9
0
17
17
0
59
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _