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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALG2 All Species: 20.3
Human Site: S16 Identified Species: 29.78
UniProt: Q9H553 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H553 NP_149078.1 416 47092 S16 R D S V P K P S V L F L H P D
Chimpanzee Pan troglodytes XP_528363 416 47103 S16 R D S V P K P S V L F L H P D
Rhesus Macaque Macaca mulatta XP_001112564 416 47090 S16 R D L V P K P S V L F L H P D
Dog Lupus familis XP_532010 416 46742 S16 P E P G P S P S V L F L H P D
Cat Felis silvestris
Mouse Mus musculus Q9DBE8 415 47386 S16 R S R V Y S P S V L F L H P D
Rat Rattus norvegicus NP_001094180 415 47300 S16 R S R V Y S P S V L F L H P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q08B22 486 54690 T15 C G M M R L L T A L F I P V L
Zebra Danio Brachydanio rerio NP_001098406 402 45631 G15 H P D L G I G G A E R L V V D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647772 424 48580 G15 H P D L G I G G A E R L V V D
Honey Bee Apis mellifera XP_624358 407 46636 G14 L H P D L G I G G A E R L V I
Nematode Worm Caenorhab. elegans NP_495010 400 45591 G15 H P D L G I G G A E R L I V D
Sea Urchin Strong. purpuratus XP_794663 401 45536 G15 H P D L G I G G A E R L V V D
Poplar Tree Populus trichocarpa XP_002317454 413 46341 D13 K I A I I H P D L G I G G A E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_178001 403 45009 P16 M N I A I I H P D L G I G G A
Baker's Yeast Sacchar. cerevisiae P43636 503 58029 D15 T I A F I H P D L G I G G A E
Red Bread Mold Neurospora crassa Q8X0H8 471 51906 P18 K T I V F L H P D L G I G G A
Conservation
Percent
Protein Identity: 100 99.7 97.1 90.3 N.A. 80.7 81.4 N.A. N.A. N.A. 21.8 65.1 N.A. 50.4 50.2 45.4 59.8
Protein Similarity: 100 99.7 99 95.1 N.A. 90.3 90.3 N.A. N.A. N.A. 39 78.6 N.A. 67.2 67.5 64.4 75.2
P-Site Identity: 100 100 93.3 66.6 N.A. 73.3 73.3 N.A. N.A. N.A. 13.3 13.3 N.A. 13.3 0 13.3 13.3
P-Site Similarity: 100 100 93.3 73.3 N.A. 73.3 73.3 N.A. N.A. N.A. 33.3 20 N.A. 20 0 20 20
Percent
Protein Identity: 44.7 N.A. N.A. 47.6 34.3 37.7
Protein Similarity: 62.7 N.A. N.A. 64.4 53 53.9
P-Site Identity: 6.6 N.A. N.A. 6.6 6.6 13.3
P-Site Similarity: 40 N.A. N.A. 20 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 7 0 0 0 0 32 7 0 0 0 13 13 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 25 7 0 0 0 13 13 0 0 0 0 0 63 % D
% Glu: 0 7 0 0 0 0 0 0 0 25 7 0 0 0 13 % E
% Phe: 0 0 0 7 7 0 0 0 0 0 44 0 0 0 0 % F
% Gly: 0 7 0 7 25 7 25 32 7 13 13 13 25 13 0 % G
% His: 25 7 0 0 0 13 13 0 0 0 0 0 38 0 0 % H
% Ile: 0 13 13 7 19 32 7 0 0 0 13 19 7 0 7 % I
% Lys: 13 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % K
% Leu: 7 0 7 25 7 13 7 0 13 57 0 63 7 0 7 % L
% Met: 7 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 25 13 0 25 0 50 13 0 0 0 0 7 38 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 32 0 13 0 7 0 0 0 0 0 25 7 0 0 0 % R
% Ser: 0 13 13 0 0 19 0 38 0 0 0 0 0 0 0 % S
% Thr: 7 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % T
% Val: 0 0 0 38 0 0 0 0 38 0 0 0 19 38 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _