Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALG2 All Species: 35.15
Human Site: S202 Identified Species: 51.56
UniProt: Q9H553 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H553 NP_149078.1 416 47092 S202 D P D V L Y P S L N V T S F D
Chimpanzee Pan troglodytes XP_528363 416 47103 S202 D P D V L Y P S L N V T S F D
Rhesus Macaque Macaca mulatta XP_001112564 416 47090 S202 D P D V L Y P S L N V T S F D
Dog Lupus familis XP_532010 416 46742 S202 E P D V L Y P S L N V T S F D
Cat Felis silvestris
Mouse Mus musculus Q9DBE8 415 47386 S202 N P D V L Y P S L N I G S F D
Rat Rattus norvegicus NP_001094180 415 47300 S202 N P D V L Y P S L N I G S F D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q08B22 486 54690 T197 G C Y V H Y P T I S M D M L S
Zebra Danio Brachydanio rerio NP_001098406 402 45631 S189 H T D V L Y P S L N S S A F D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647772 424 48580 L191 P D V L Y P S L H T Q Y F D Q
Honey Bee Apis mellifera XP_624358 407 46636 I186 P E V L Y P S I N T D F F D K
Nematode Worm Caenorhab. elegans NP_495010 400 45591 S185 E L T V L Y P S L N T E F F D
Sea Urchin Strong. purpuratus XP_794663 401 45536 S187 Q P D V L Y P S L N F S A F N
Poplar Tree Populus trichocarpa XP_002317454 413 46341 Y190 G I R P A V L Y P A V N V D Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_178001 403 45009 L183 F A N T F K R L N A Q G S R P
Baker's Yeast Sacchar. cerevisiae P43636 503 58029 V194 P D V I Y P C V D L S T I E I
Red Bread Mold Neurospora crassa Q8X0H8 471 51906 P204 R S L E V V H P C I D V R S T
Conservation
Percent
Protein Identity: 100 99.7 97.1 90.3 N.A. 80.7 81.4 N.A. N.A. N.A. 21.8 65.1 N.A. 50.4 50.2 45.4 59.8
Protein Similarity: 100 99.7 99 95.1 N.A. 90.3 90.3 N.A. N.A. N.A. 39 78.6 N.A. 67.2 67.5 64.4 75.2
P-Site Identity: 100 100 100 93.3 N.A. 80 80 N.A. N.A. N.A. 20 66.6 N.A. 0 0 60 66.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. 46.6 80 N.A. 6.6 6.6 66.6 86.6
Percent
Protein Identity: 44.7 N.A. N.A. 47.6 34.3 37.7
Protein Similarity: 62.7 N.A. N.A. 64.4 53 53.9
P-Site Identity: 6.6 N.A. N.A. 6.6 6.6 0
P-Site Similarity: 6.6 N.A. N.A. 13.3 13.3 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 7 0 0 0 0 13 0 0 13 0 0 % A
% Cys: 0 7 0 0 0 0 7 0 7 0 0 0 0 0 0 % C
% Asp: 19 13 50 0 0 0 0 0 7 0 13 7 0 19 50 % D
% Glu: 13 7 0 7 0 0 0 0 0 0 0 7 0 7 0 % E
% Phe: 7 0 0 0 7 0 0 0 0 0 7 7 19 57 0 % F
% Gly: 13 0 0 0 0 0 0 0 0 0 0 19 0 0 0 % G
% His: 7 0 0 0 7 0 7 0 7 0 0 0 0 0 0 % H
% Ile: 0 7 0 7 0 0 0 7 7 7 13 0 7 0 7 % I
% Lys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 7 % K
% Leu: 0 7 7 13 57 0 7 13 57 7 0 0 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 0 % M
% Asn: 13 0 7 0 0 0 0 0 13 57 0 7 0 0 7 % N
% Pro: 19 44 0 7 0 19 63 7 7 0 0 0 0 0 7 % P
% Gln: 7 0 0 0 0 0 0 0 0 0 13 0 0 0 13 % Q
% Arg: 7 0 7 0 0 0 7 0 0 0 0 0 7 7 0 % R
% Ser: 0 7 0 0 0 0 13 57 0 7 13 13 44 7 7 % S
% Thr: 0 7 7 7 0 0 0 7 0 13 7 32 0 0 7 % T
% Val: 0 0 19 63 7 13 0 7 0 0 32 7 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 19 63 0 7 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _