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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALG2
All Species:
32.12
Human Site:
S310
Identified Species:
47.11
UniProt:
Q9H553
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H553
NP_149078.1
416
47092
S310
F
S
D
K
Q
K
I
S
L
L
H
S
C
T
C
Chimpanzee
Pan troglodytes
XP_528363
416
47103
S310
F
S
D
K
Q
K
I
S
L
L
H
S
C
T
C
Rhesus Macaque
Macaca mulatta
XP_001112564
416
47090
S310
F
S
D
K
Q
K
I
S
L
L
H
S
C
T
C
Dog
Lupus familis
XP_532010
416
46742
S310
F
S
D
K
Q
K
I
S
L
L
H
G
C
T
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBE8
415
47386
S310
F
S
D
R
Q
K
I
S
L
L
H
G
C
L
C
Rat
Rattus norvegicus
NP_001094180
415
47300
S310
F
S
D
R
Q
K
I
S
L
L
H
G
C
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q08B22
486
54690
K377
V
P
F
E
E
L
K
K
H
L
S
E
A
T
I
Zebra Danio
Brachydanio rerio
NP_001098406
402
45631
S296
F
S
D
K
Q
K
L
S
L
L
H
N
S
T
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647772
424
48580
R307
P
T
D
E
E
K
C
R
L
L
F
A
A
H
C
Honey Bee
Apis mellifera
XP_624358
407
46636
S296
P
S
D
I
D
K
I
S
I
L
H
H
C
K
I
Nematode Worm
Caenorhab. elegans
NP_495010
400
45591
N295
P
S
D
T
Q
K
V
N
L
I
R
R
S
R
A
Sea Urchin
Strong. purpuratus
XP_794663
401
45536
T294
F
S
D
A
Q
K
L
T
L
L
D
S
C
T
C
Poplar Tree
Populus trichocarpa
XP_002317454
413
46341
K303
C
S
T
A
E
R
N
K
L
L
S
Q
C
L
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_178001
403
45009
E292
C
S
T
A
E
R
N
E
L
L
S
S
C
L
C
Baker's Yeast
Sacchar. cerevisiae
P43636
503
58029
L320
I
S
S
S
L
K
E
L
L
L
E
R
T
E
M
Red Bread Mold
Neurospora crassa
Q8X0H8
471
51906
I330
V
P
N
T
L
K
E
I
L
L
R
S
A
K
L
Conservation
Percent
Protein Identity:
100
99.7
97.1
90.3
N.A.
80.7
81.4
N.A.
N.A.
N.A.
21.8
65.1
N.A.
50.4
50.2
45.4
59.8
Protein Similarity:
100
99.7
99
95.1
N.A.
90.3
90.3
N.A.
N.A.
N.A.
39
78.6
N.A.
67.2
67.5
64.4
75.2
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
N.A.
N.A.
13.3
80
N.A.
33.3
53.3
33.3
73.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
26.6
93.3
N.A.
60
60
53.3
86.6
Percent
Protein Identity:
44.7
N.A.
N.A.
47.6
34.3
37.7
Protein Similarity:
62.7
N.A.
N.A.
64.4
53
53.9
P-Site Identity:
33.3
N.A.
N.A.
40
26.6
26.6
P-Site Similarity:
46.6
N.A.
N.A.
53.3
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
0
0
0
0
0
0
7
19
0
7
% A
% Cys:
13
0
0
0
0
0
7
0
0
0
0
0
63
0
69
% C
% Asp:
0
0
69
0
7
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
0
0
0
13
25
0
13
7
0
0
7
7
0
7
0
% E
% Phe:
50
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
50
7
0
7
0
% H
% Ile:
7
0
0
7
0
0
44
7
7
7
0
0
0
0
13
% I
% Lys:
0
0
0
32
0
82
7
13
0
0
0
0
0
13
0
% K
% Leu:
0
0
0
0
13
7
13
7
88
94
0
0
0
25
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
7
0
0
0
13
7
0
0
0
7
0
0
0
% N
% Pro:
19
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
57
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
0
0
13
0
13
0
7
0
0
13
13
0
7
0
% R
% Ser:
0
82
7
7
0
0
0
50
0
0
19
38
13
0
0
% S
% Thr:
0
7
13
13
0
0
0
7
0
0
0
0
7
44
0
% T
% Val:
13
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _