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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALG2
All Species:
22.73
Human Site:
T255
Identified Species:
33.33
UniProt:
Q9H553
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H553
NP_149078.1
416
47092
T255
V
Q
L
R
G
R
L
T
S
Q
D
W
E
R
V
Chimpanzee
Pan troglodytes
XP_528363
416
47103
T255
V
Q
L
R
G
R
L
T
S
Q
D
W
E
R
V
Rhesus Macaque
Macaca mulatta
XP_001112564
416
47090
T255
V
Q
L
R
G
R
L
T
S
Q
D
W
E
R
V
Dog
Lupus familis
XP_532010
416
46742
T255
V
K
L
R
G
R
L
T
S
Q
D
W
D
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBE8
415
47386
P255
V
Q
L
R
N
R
L
P
S
Q
E
W
D
K
V
Rat
Rattus norvegicus
NP_001094180
415
47300
P255
V
Q
L
R
A
R
L
P
P
Q
E
W
E
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q08B22
486
54690
L322
I
R
A
F
A
A
L
L
E
K
K
T
A
E
Q
Zebra Danio
Brachydanio rerio
NP_001098406
402
45631
S241
A
N
L
K
D
R
L
S
V
G
E
W
E
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647772
424
48580
P252
R
L
L
G
D
M
L
P
A
T
D
F
K
R
C
Honey Bee
Apis mellifera
XP_624358
407
46636
T241
A
E
L
Q
K
Y
L
T
E
E
E
Y
K
K
V
Nematode Worm
Caenorhab. elegans
NP_495010
400
45591
A240
K
L
K
S
N
L
P
A
D
E
F
S
Q
C
H
Sea Urchin
Strong. purpuratus
XP_794663
401
45536
S239
G
E
L
K
S
R
L
S
E
D
E
W
Q
N
V
Poplar Tree
Populus trichocarpa
XP_002317454
413
46341
L248
Q
K
L
N
E
A
T
L
T
I
A
G
K
S
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_178001
403
45009
H237
A
F
A
I
L
C
K
H
K
Q
N
L
S
D
V
Baker's Yeast
Sacchar. cerevisiae
P43636
503
58029
N265
Y
D
E
R
V
A
E
N
V
E
Y
L
K
E
L
Red Bread Mold
Neurospora crassa
Q8X0H8
471
51906
R275
I
A
G
G
Y
D
N
R
V
H
E
N
V
S
Y
Conservation
Percent
Protein Identity:
100
99.7
97.1
90.3
N.A.
80.7
81.4
N.A.
N.A.
N.A.
21.8
65.1
N.A.
50.4
50.2
45.4
59.8
Protein Similarity:
100
99.7
99
95.1
N.A.
90.3
90.3
N.A.
N.A.
N.A.
39
78.6
N.A.
67.2
67.5
64.4
75.2
P-Site Identity:
100
100
100
80
N.A.
66.6
66.6
N.A.
N.A.
N.A.
6.6
40
N.A.
26.6
26.6
0
33.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
80
N.A.
N.A.
N.A.
26.6
60
N.A.
46.6
73.3
13.3
66.6
Percent
Protein Identity:
44.7
N.A.
N.A.
47.6
34.3
37.7
Protein Similarity:
62.7
N.A.
N.A.
64.4
53
53.9
P-Site Identity:
6.6
N.A.
N.A.
13.3
6.6
0
P-Site Similarity:
26.6
N.A.
N.A.
20
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
7
13
0
13
19
0
7
7
0
7
0
7
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
13
7
% C
% Asp:
0
7
0
0
13
7
0
0
7
7
32
0
13
7
0
% D
% Glu:
0
13
7
0
7
0
7
0
19
19
38
0
32
13
0
% E
% Phe:
0
7
0
7
0
0
0
0
0
0
7
7
0
0
0
% F
% Gly:
7
0
7
13
25
0
0
0
0
7
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
7
% H
% Ile:
13
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
7
13
7
13
7
0
7
0
7
7
7
0
25
25
0
% K
% Leu:
0
13
69
0
7
7
69
13
0
0
0
13
0
0
7
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
7
13
0
7
7
0
0
7
7
0
7
0
% N
% Pro:
0
0
0
0
0
0
7
19
7
0
0
0
0
0
0
% P
% Gln:
7
32
0
7
0
0
0
0
0
44
0
0
13
0
13
% Q
% Arg:
7
7
0
44
0
50
0
7
0
0
0
0
0
25
0
% R
% Ser:
0
0
0
7
7
0
0
13
32
0
0
7
7
13
0
% S
% Thr:
0
0
0
0
0
0
7
32
7
7
0
7
0
0
0
% T
% Val:
38
0
0
0
7
0
0
0
19
0
0
0
7
0
63
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% W
% Tyr:
7
0
0
0
7
7
0
0
0
0
7
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _