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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALG2
All Species:
33.64
Human Site:
Y200
Identified Species:
49.33
UniProt:
Q9H553
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H553
NP_149078.1
416
47092
Y200
H
I
D
P
D
V
L
Y
P
S
L
N
V
T
S
Chimpanzee
Pan troglodytes
XP_528363
416
47103
Y200
H
I
D
P
D
V
L
Y
P
S
L
N
V
T
S
Rhesus Macaque
Macaca mulatta
XP_001112564
416
47090
Y200
H
I
D
P
D
V
L
Y
P
S
L
N
V
T
S
Dog
Lupus familis
XP_532010
416
46742
Y200
H
I
E
P
D
V
L
Y
P
S
L
N
V
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBE8
415
47386
Y200
H
R
N
P
D
V
L
Y
P
S
L
N
I
G
S
Rat
Rattus norvegicus
NP_001094180
415
47300
Y200
H
R
N
P
D
V
L
Y
P
S
L
N
I
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q08B22
486
54690
Y195
H
V
G
C
Y
V
H
Y
P
T
I
S
M
D
M
Zebra Danio
Brachydanio rerio
NP_001098406
402
45631
Y187
K
I
H
T
D
V
L
Y
P
S
L
N
S
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647772
424
48580
P189
T
V
P
D
V
L
Y
P
S
L
H
T
Q
Y
F
Honey Bee
Apis mellifera
XP_624358
407
46636
P184
I
E
P
E
V
L
Y
P
S
I
N
T
D
F
F
Nematode Worm
Caenorhab. elegans
NP_495010
400
45591
Y183
S
Q
E
L
T
V
L
Y
P
S
L
N
T
E
F
Sea Urchin
Strong. purpuratus
XP_794663
401
45536
Y185
D
V
Q
P
D
V
L
Y
P
S
L
N
F
S
A
Poplar Tree
Populus trichocarpa
XP_002317454
413
46341
V188
A
R
G
I
R
P
A
V
L
Y
P
A
V
N
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_178001
403
45009
K181
S
T
F
A
N
T
F
K
R
L
N
A
Q
G
S
Baker's Yeast
Sacchar. cerevisiae
P43636
503
58029
P192
N
D
P
D
V
I
Y
P
C
V
D
L
S
T
I
Red Bread Mold
Neurospora crassa
Q8X0H8
471
51906
V202
S
K
R
S
L
E
V
V
H
P
C
I
D
V
R
Conservation
Percent
Protein Identity:
100
99.7
97.1
90.3
N.A.
80.7
81.4
N.A.
N.A.
N.A.
21.8
65.1
N.A.
50.4
50.2
45.4
59.8
Protein Similarity:
100
99.7
99
95.1
N.A.
90.3
90.3
N.A.
N.A.
N.A.
39
78.6
N.A.
67.2
67.5
64.4
75.2
P-Site Identity:
100
100
100
93.3
N.A.
73.3
73.3
N.A.
N.A.
N.A.
26.6
60
N.A.
0
0
46.6
60
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
N.A.
60
73.3
N.A.
13.3
6.6
53.3
80
Percent
Protein Identity:
44.7
N.A.
N.A.
47.6
34.3
37.7
Protein Similarity:
62.7
N.A.
N.A.
64.4
53
53.9
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
6.6
N.A.
N.A.
13.3
20
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
7
0
0
0
0
13
0
0
13
% A
% Cys:
0
0
0
7
0
0
0
0
7
0
7
0
0
0
0
% C
% Asp:
7
7
19
13
50
0
0
0
0
0
7
0
13
7
0
% D
% Glu:
0
7
13
7
0
7
0
0
0
0
0
0
0
7
0
% E
% Phe:
0
0
7
0
0
0
7
0
0
0
0
0
7
7
19
% F
% Gly:
0
0
13
0
0
0
0
0
0
0
0
0
0
19
0
% G
% His:
44
0
7
0
0
0
7
0
7
0
7
0
0
0
0
% H
% Ile:
7
32
0
7
0
7
0
0
0
7
7
7
13
0
7
% I
% Lys:
7
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
7
7
13
57
0
7
13
57
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% M
% Asn:
7
0
13
0
7
0
0
0
0
0
13
57
0
7
0
% N
% Pro:
0
0
19
44
0
7
0
19
63
7
7
0
0
0
0
% P
% Gln:
0
7
7
0
0
0
0
0
0
0
0
0
13
0
0
% Q
% Arg:
0
19
7
0
7
0
0
0
7
0
0
0
0
0
7
% R
% Ser:
19
0
0
7
0
0
0
0
13
57
0
7
13
13
44
% S
% Thr:
7
7
0
7
7
7
0
0
0
7
0
13
7
32
0
% T
% Val:
0
19
0
0
19
63
7
13
0
7
0
0
32
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
19
63
0
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _