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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP21
All Species:
2.42
Human Site:
S126
Identified Species:
5.33
UniProt:
Q9H596
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H596
NP_071359.3
190
21529
S126
A
Y
L
M
K
Y
H
S
M
S
L
L
D
A
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088878
189
21042
M126
Y
L
M
K
Y
H
S
M
S
L
L
D
A
H
A
Dog
Lupus familis
XP_548963
287
32553
A223
A
Y
L
M
K
Y
H
A
L
S
L
L
D
A
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE01
188
21100
S126
L
M
K
Y
H
A
M
S
L
V
D
A
H
T
W
Rat
Rattus norvegicus
Q6AXW7
204
22736
S126
L
M
K
Y
H
V
M
S
L
L
D
A
H
A
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521266
188
20903
S126
L
M
K
Y
H
A
M
S
L
L
D
A
H
A
W
Chicken
Gallus gallus
XP_415295
179
19834
L119
M
K
H
H
A
M
S
L
A
S
A
H
A
W
V
Frog
Xenopus laevis
NP_001086177
209
23606
R141
A
Y
L
M
K
Y
H
R
L
A
L
L
D
A
Y
Zebra Danio
Brachydanio rerio
NP_001006060
221
24974
R154
A
Y
L
M
K
Y
H
R
V
S
L
A
E
A
H
Tiger Blowfish
Takifugu rubipres
P0C599
210
23683
H126
H
P
A
A
Q
F
I
H
E
A
L
S
Q
P
H
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791539
182
20339
K122
K
Y
E
H
L
T
L
K
Q
A
H
V
H
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
91
47.7
N.A.
66.8
66.6
N.A.
64.7
50.5
46.4
44.3
28.5
N.A.
N.A.
N.A.
37.8
Protein Similarity:
100
N.A.
96.8
56.4
N.A.
84.7
77.9
N.A.
81.5
70.5
64.5
60.1
45.7
N.A.
N.A.
N.A.
60
P-Site Identity:
100
N.A.
6.6
86.6
N.A.
6.6
13.3
N.A.
13.3
6.6
73.3
73.3
13.3
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
20
100
N.A.
13.3
20
N.A.
20
6.6
93.3
86.6
33.3
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
0
10
10
10
19
0
10
10
28
10
37
19
55
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
28
10
28
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
10
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
10
19
28
10
37
10
0
0
10
10
37
10
37
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
28
10
37
0
0
10
0
0
0
0
0
0
10
% K
% Leu:
28
10
37
0
10
0
10
10
46
28
55
28
0
0
0
% L
% Met:
10
28
10
37
0
10
28
10
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
10
0
0
0
10
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
19
37
10
37
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
10
0
0
10
10
0
10
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
28
% W
% Tyr:
10
46
0
28
10
37
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _