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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP21
All Species:
3.03
Human Site:
T74
Identified Species:
6.67
UniProt:
Q9H596
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H596
NP_071359.3
190
21529
T74
Q
Y
I
K
V
P
V
T
D
A
R
D
S
R
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088878
189
21042
D74
Y
V
K
V
P
V
T
D
A
R
D
S
R
L
C
Dog
Lupus familis
XP_548963
287
32553
A171
Q
Y
V
Q
V
P
V
A
D
A
P
S
S
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE01
188
21100
A74
V
Q
V
P
V
V
D
A
P
V
A
R
L
S
N
Rat
Rattus norvegicus
Q6AXW7
204
22736
A74
V
Q
V
P
V
V
D
A
P
I
A
R
L
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521266
188
20903
T74
V
Q
V
P
V
A
D
T
P
L
S
R
L
C
D
Chicken
Gallus gallus
XP_415295
179
19834
P67
R
I
P
V
A
D
S
P
T
A
R
I
S
A
C
Frog
Xenopus laevis
NP_001086177
209
23606
P89
D
Y
M
K
V
P
V
P
D
L
P
H
A
P
L
Zebra Danio
Brachydanio rerio
NP_001006060
221
24974
A102
E
Y
V
K
V
P
L
A
D
M
P
H
S
P
I
Tiger Blowfish
Takifugu rubipres
P0C599
210
23683
T74
G
L
R
D
L
G
I
T
H
V
L
N
A
A
E
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791539
182
20339
T70
I
A
V
D
D
I
P
T
A
Q
L
G
V
H
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
91
47.7
N.A.
66.8
66.6
N.A.
64.7
50.5
46.4
44.3
28.5
N.A.
N.A.
N.A.
37.8
Protein Similarity:
100
N.A.
96.8
56.4
N.A.
84.7
77.9
N.A.
81.5
70.5
64.5
60.1
45.7
N.A.
N.A.
N.A.
60
P-Site Identity:
100
N.A.
0
66.6
N.A.
6.6
6.6
N.A.
13.3
20
46.6
40
6.6
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
0
80
N.A.
13.3
13.3
N.A.
20
26.6
60
66.6
33.3
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
10
0
37
19
28
19
0
19
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
19
% C
% Asp:
10
0
0
19
10
10
28
10
37
0
10
10
0
0
19
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
19
0
10
0
% H
% Ile:
10
10
10
0
0
10
10
0
0
10
0
10
0
0
10
% I
% Lys:
0
0
10
28
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
10
0
10
0
0
19
19
0
28
10
28
% L
% Met:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% N
% Pro:
0
0
10
28
10
37
10
19
28
0
28
0
0
19
0
% P
% Gln:
19
28
0
10
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
10
0
10
0
0
0
0
0
0
10
19
28
10
19
0
% R
% Ser:
0
0
0
0
0
0
10
0
0
0
10
19
37
19
0
% S
% Thr:
0
0
0
0
0
0
10
37
10
0
0
0
0
0
0
% T
% Val:
28
10
55
19
64
28
28
0
0
19
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
37
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _