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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUV39H2 All Species: 19.09
Human Site: S388 Identified Species: 35
UniProt: Q9H5I1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H5I1 NP_078946.1 410 46682 S388 S S D S I D H S P A K K R V R
Chimpanzee Pan troglodytes XP_001147642 410 46749 S388 S S D S I D H S P A K K R V R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535179 410 46607 S388 S S D S V D H S P A K K R V R
Cat Felis silvestris
Mouse Mus musculus Q9EQQ0 477 54079 S455 S S D S I D H S P A K K R V R
Rat Rattus norvegicus Q5I0M0 315 35011 S294 P C Y C G A Q S C A T F L P Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515560 415 47688 S393 S S E S I D L S P A K K R V R
Chicken Gallus gallus Q5F3W5 407 46641 L384 T S D S A D G L S S S R K R I
Frog Xenopus laevis Q6NRE8 421 48563 S390 V E S S K M D S N F G I A G L
Zebra Danio Brachydanio rerio Q6DGD3 411 47452 L380 A E S T K M D L D F S R A G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P45975 635 71885 E613 D N E D V P Y E N L S T A V R
Honey Bee Apis mellifera NP_001035367 683 78686 A637 E N S I M Q R A S M K E N L N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782949 324 36247 A303 G S V N E E G A N E L A Q V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q8X225 331 37553 P310 L E S D A H D P S K I S E M T
Conservation
Percent
Protein Identity: 100 99.7 N.A. 97.8 N.A. 76.9 26.1 N.A. 85.3 77.5 58.1 55.4 N.A. 30.3 32.5 N.A. 44.3
Protein Similarity: 100 99.7 N.A. 98.5 N.A. 81.3 39.2 N.A. 91.5 87.5 70.5 70.3 N.A. 43.7 43.4 N.A. 57.5
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 13.3 N.A. 86.6 26.6 13.3 0 N.A. 13.3 6.6 N.A. 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 13.3 N.A. 93.3 53.3 13.3 20 N.A. 40 40 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 28.5
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 44.8
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 16 8 0 16 0 47 0 8 24 0 0 % A
% Cys: 0 8 0 8 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 8 0 39 16 0 47 24 0 8 0 0 0 0 0 0 % D
% Glu: 8 24 16 0 8 8 0 8 0 8 0 8 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 16 0 8 0 0 0 % F
% Gly: 8 0 0 0 8 0 16 0 0 0 8 0 0 16 0 % G
% His: 0 0 0 0 0 8 31 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 31 0 0 0 0 0 8 8 0 0 16 % I
% Lys: 0 0 0 0 16 0 0 0 0 8 47 39 8 0 0 % K
% Leu: 8 0 0 0 0 0 8 16 0 8 8 0 8 8 8 % L
% Met: 0 0 0 0 8 16 0 0 0 8 0 0 0 8 0 % M
% Asn: 0 16 0 8 0 0 0 0 24 0 0 0 8 0 8 % N
% Pro: 8 0 0 0 0 8 0 8 39 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 8 8 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 16 39 8 47 % R
% Ser: 39 54 31 54 0 0 0 54 24 8 24 8 0 0 0 % S
% Thr: 8 0 0 8 0 0 0 0 0 0 8 8 0 0 8 % T
% Val: 8 0 8 0 16 0 0 0 0 0 0 0 0 54 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _