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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC4
All Species:
20.3
Human Site:
S388
Identified Species:
40.61
UniProt:
Q9H5U6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H5U6
NP_079212.2
513
59010
S388
S
P
C
Q
R
Y
V
S
L
E
N
Q
H
C
E
Chimpanzee
Pan troglodytes
XP_517131
511
58772
S386
S
L
C
Q
R
Y
V
S
L
E
N
Q
H
C
E
Rhesus Macaque
Macaca mulatta
XP_001082520
513
59132
S388
S
L
C
Q
R
Y
V
S
L
E
N
Q
H
C
E
Dog
Lupus familis
XP_536271
532
61239
S407
P
L
C
Q
R
Y
I
S
L
E
N
Q
H
C
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKW4
512
58549
S386
S
L
C
Q
R
Y
V
S
R
E
N
Q
H
C
V
Rat
Rattus norvegicus
NP_001101830
273
31755
E156
N
K
I
I
L
P
S
E
E
G
Y
R
F
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513839
467
53949
P351
V
R
I
F
S
N
I
P
P
N
K
I
I
L
P
Chicken
Gallus gallus
XP_420756
505
57892
S378
A
I
C
Q
R
Y
V
S
S
G
N
H
H
C
E
Frog
Xenopus laevis
Q6DCD7
489
56017
R371
R
F
C
S
V
C
E
R
F
V
C
S
E
N
K
Zebra Danio
Brachydanio rerio
NP_001107071
484
55873
Y368
I
L
P
E
A
E
G
Y
R
F
C
S
V
C
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610973
437
51065
L320
C
Y
T
A
K
E
N
L
H
C
N
R
C
G
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178580
620
69498
H373
C
V
K
P
S
F
S
H
C
T
K
C
N
M
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
97.2
83.4
N.A.
75.6
45.2
N.A.
73
61.4
61.9
54.7
N.A.
31.7
N.A.
N.A.
30.6
Protein Similarity:
100
99
98.2
87.2
N.A.
84.4
49.9
N.A.
79.9
74.6
73.6
68
N.A.
46.7
N.A.
N.A.
45.6
P-Site Identity:
100
93.3
93.3
80
N.A.
80
6.6
N.A.
0
66.6
6.6
13.3
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
80
20
N.A.
6.6
73.3
13.3
20
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
17
0
59
0
0
9
0
0
9
9
17
9
9
67
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
17
9
9
9
42
0
0
9
0
50
% E
% Phe:
0
9
0
9
0
9
0
0
9
9
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
17
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
9
9
0
0
9
50
0
0
% H
% Ile:
9
9
17
9
0
0
17
0
0
0
0
9
9
0
0
% I
% Lys:
0
9
9
0
9
0
0
0
0
0
17
0
0
0
17
% K
% Leu:
0
42
0
0
9
0
0
9
34
0
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
0
0
0
0
9
9
0
0
9
59
0
9
9
0
% N
% Pro:
9
9
9
9
0
9
0
9
9
0
0
0
0
0
9
% P
% Gln:
0
0
0
50
0
0
0
0
0
0
0
42
0
0
0
% Q
% Arg:
9
9
0
0
50
0
0
9
17
0
0
17
0
0
0
% R
% Ser:
34
0
0
9
17
0
17
50
9
0
0
17
0
0
9
% S
% Thr:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
9
9
0
0
9
0
42
0
0
9
0
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
50
0
9
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _