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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC4
All Species:
15.15
Human Site:
S496
Identified Species:
30.3
UniProt:
Q9H5U6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H5U6
NP_079212.2
513
59010
S496
G
Q
S
M
N
H
T
S
A
T
R
R
K
K
R
Chimpanzee
Pan troglodytes
XP_517131
511
58772
S494
G
Q
S
M
N
H
T
S
A
T
R
R
K
K
R
Rhesus Macaque
Macaca mulatta
XP_001082520
513
59132
S496
G
Q
S
M
N
H
T
S
A
T
R
R
K
K
R
Dog
Lupus familis
XP_536271
532
61239
S515
G
Q
S
M
N
H
T
S
V
T
R
K
K
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKW4
512
58549
L494
A
I
Y
R
S
T
K
L
S
E
D
S
E
F
F
Rat
Rattus norvegicus
NP_001101830
273
31755
K257
N
N
A
V
R
K
Q
K
Q
R
K
S
N
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513839
467
53949
K451
C
P
N
R
S
K
H
K
K
T
V
K
A
V
R
Chicken
Gallus gallus
XP_420756
505
57892
A486
L
G
V
C
K
R
W
A
M
K
Y
A
V
F
S
Frog
Xenopus laevis
Q6DCD7
489
56017
Q472
I
K
G
N
M
K
K
Q
P
T
A
T
T
S
K
Zebra Danio
Brachydanio rerio
NP_001107071
484
55873
H468
G
A
P
G
L
S
K
H
K
A
G
K
S
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610973
437
51065
S420
E
K
R
C
S
Y
R
S
K
Y
F
R
E
Q
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178580
620
69498
R587
T
Q
D
V
R
K
G
R
V
D
G
K
K
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
97.2
83.4
N.A.
75.6
45.2
N.A.
73
61.4
61.9
54.7
N.A.
31.7
N.A.
N.A.
30.6
Protein Similarity:
100
99
98.2
87.2
N.A.
84.4
49.9
N.A.
79.9
74.6
73.6
68
N.A.
46.7
N.A.
N.A.
45.6
P-Site Identity:
100
100
100
80
N.A.
0
6.6
N.A.
13.3
0
6.6
6.6
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
20
26.6
N.A.
33.3
6.6
20
20
N.A.
46.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
0
0
0
0
9
25
9
9
9
9
0
9
% A
% Cys:
9
0
0
17
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
9
0
0
0
0
0
0
9
9
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
9
0
0
17
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
17
9
% F
% Gly:
42
9
9
9
0
0
9
0
0
0
17
0
0
0
0
% G
% His:
0
0
0
0
0
34
9
9
0
0
0
0
0
0
0
% H
% Ile:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
17
0
0
9
34
25
17
25
9
9
34
42
34
9
% K
% Leu:
9
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
34
9
0
0
0
9
0
0
0
0
9
0
% M
% Asn:
9
9
9
9
34
0
0
0
0
0
0
0
9
9
0
% N
% Pro:
0
9
9
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
42
0
0
0
0
9
9
9
0
0
0
0
9
0
% Q
% Arg:
0
0
9
17
17
9
9
9
0
9
34
34
0
9
42
% R
% Ser:
0
0
34
0
25
9
0
42
9
0
0
17
9
9
17
% S
% Thr:
9
0
0
0
0
9
34
0
0
50
0
9
9
0
0
% T
% Val:
0
0
9
17
0
0
0
0
17
0
9
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
9
0
0
0
9
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _