KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC4
All Species:
19.7
Human Site:
T120
Identified Species:
39.39
UniProt:
Q9H5U6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H5U6
NP_079212.2
513
59010
T120
K
F
I
E
L
P
L
T
Q
R
K
F
C
Q
T
Chimpanzee
Pan troglodytes
XP_517131
511
58772
T120
K
F
I
E
L
P
L
T
Q
R
K
F
C
Q
T
Rhesus Macaque
Macaca mulatta
XP_001082520
513
59132
T120
K
F
I
E
L
P
L
T
Q
R
K
F
C
Q
R
Dog
Lupus familis
XP_536271
532
61239
S139
K
F
I
E
L
P
L
S
Q
R
K
F
C
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKW4
512
58549
A119
S
F
I
Q
L
P
L
A
Q
R
K
F
C
Q
S
Rat
Rattus norvegicus
NP_001101830
273
31755
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513839
467
53949
S89
R
S
C
Q
P
P
L
S
H
V
Q
Y
V
E
R
Chicken
Gallus gallus
XP_420756
505
57892
S110
N
F
V
L
L
P
L
S
K
R
R
F
C
Q
E
Frog
Xenopus laevis
Q6DCD7
489
56017
A108
E
F
T
A
L
P
L
A
K
R
K
F
C
C
D
Zebra Danio
Brachydanio rerio
NP_001107071
484
55873
S106
S
R
F
L
E
F
A
S
L
P
L
E
Q
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610973
437
51065
C58
A
H
R
D
S
K
L
C
N
Y
H
L
P
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178580
620
69498
D109
T
T
E
S
L
A
E
D
E
R
T
F
C
Y
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
97.2
83.4
N.A.
75.6
45.2
N.A.
73
61.4
61.9
54.7
N.A.
31.7
N.A.
N.A.
30.6
Protein Similarity:
100
99
98.2
87.2
N.A.
84.4
49.9
N.A.
79.9
74.6
73.6
68
N.A.
46.7
N.A.
N.A.
45.6
P-Site Identity:
100
100
93.3
86.6
N.A.
73.3
0
N.A.
13.3
53.3
53.3
0
N.A.
6.6
N.A.
N.A.
26.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
0
N.A.
53.3
80
66.6
13.3
N.A.
13.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
9
9
17
0
0
0
0
0
9
0
% A
% Cys:
0
0
9
0
0
0
0
9
0
0
0
0
67
9
0
% C
% Asp:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
25
% D
% Glu:
9
0
9
34
9
0
9
0
9
0
0
9
0
9
9
% E
% Phe:
0
59
9
0
0
9
0
0
0
0
0
67
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
9
0
9
0
0
0
0
% H
% Ile:
0
0
42
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
34
0
0
0
0
9
0
0
17
0
50
0
0
0
0
% K
% Leu:
0
0
0
17
67
0
75
0
9
0
9
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
67
0
0
0
9
0
0
9
0
0
% P
% Gln:
0
0
0
17
0
0
0
0
42
0
9
0
9
50
0
% Q
% Arg:
9
9
9
0
0
0
0
0
0
67
9
0
0
9
34
% R
% Ser:
17
9
0
9
9
0
0
34
0
0
0
0
0
0
9
% S
% Thr:
9
9
9
0
0
0
0
25
0
0
9
0
0
0
17
% T
% Val:
0
0
9
0
0
0
0
0
0
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _