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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IKZF5 All Species: 21.52
Human Site: S174 Identified Species: 67.62
UniProt: Q9H5V7 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H5V7 NP_071911.3 419 46510 S174 K G T R S S L S S K K M W G V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082479 447 50964 F181 N N I S L V P F E R P A V I E
Dog Lupus familis XP_853942 453 50597 S208 K G T R S S L S S K K M W G V
Cat Felis silvestris
Mouse Mus musculus Q8BU00 419 46381 S174 K G T R S S L S S K K M W G V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510537 419 46295 S174 K G T R S S L S S K K M W G V
Chicken Gallus gallus Q5ZLR2 421 46924 S174 K G T R S S L S S K K M W G V
Frog Xenopus laevis Q6NRM0 453 49949 G193 K G T R P S L G N K K M W G V
Zebra Danio Brachydanio rerio Q6DBW0 419 46136 S171 K G A R S A L S H R K M L S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 21.9 91.1 N.A. 96.9 N.A. N.A. 94.5 92.6 80.1 69.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 41.1 91.6 N.A. 98.8 N.A. N.A. 95.9 96.1 84.5 82.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 0 100 N.A. 100 N.A. N.A. 100 100 80 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 6.6 100 N.A. 100 N.A. N.A. 100 100 86.6 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 0 13 0 0 0 0 0 13 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 13 % E
% Phe: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % F
% Gly: 0 88 0 0 0 0 0 13 0 0 0 0 0 75 0 % G
% His: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % H
% Ile: 0 0 13 0 0 0 0 0 0 0 0 0 0 13 0 % I
% Lys: 88 0 0 0 0 0 0 0 0 75 88 0 0 0 0 % K
% Leu: 0 0 0 0 13 0 88 0 0 0 0 0 13 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 88 0 0 0 % M
% Asn: 13 13 0 0 0 0 0 0 13 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 13 0 13 0 0 0 13 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 88 0 0 0 0 0 25 0 0 0 0 0 % R
% Ser: 0 0 0 13 75 75 0 75 63 0 0 0 0 13 0 % S
% Thr: 0 0 75 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 13 0 0 0 0 0 0 13 0 88 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 75 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _