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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IKZF5
All Species:
13.33
Human Site:
S226
Identified Species:
41.9
UniProt:
Q9H5V7
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H5V7
NP_071911.3
419
46510
S226
I
P
N
I
Q
T
D
S
Y
E
S
M
A
K
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082479
447
50964
M233
Y
E
K
E
A
E
L
M
Q
S
H
M
M
D
Q
Dog
Lupus familis
XP_853942
453
50597
S260
I
P
N
I
Q
T
D
S
Y
E
S
M
A
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU00
419
46381
S226
I
P
N
I
Q
T
D
S
Y
E
A
M
A
K
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510537
419
46295
T226
I
P
N
I
Q
T
D
T
Y
E
S
M
A
K
T
Chicken
Gallus gallus
Q5ZLR2
421
46924
A226
I
P
N
I
Q
T
E
A
Y
E
S
M
T
K
S
Frog
Xenopus laevis
Q6NRM0
453
49949
A245
I
P
S
I
Q
S
E
A
Y
E
H
L
A
K
A
Zebra Danio
Brachydanio rerio
Q6DBW0
419
46136
H223
F
T
H
D
L
P
P
H
A
H
L
H
Q
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
21.9
91.1
N.A.
96.9
N.A.
N.A.
94.5
92.6
80.1
69.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
41.1
91.6
N.A.
98.8
N.A.
N.A.
95.9
96.1
84.5
82.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
93.3
N.A.
N.A.
93.3
73.3
53.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
6.6
93.3
N.A.
100
N.A.
N.A.
100
93.3
86.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
0
25
13
0
13
0
63
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
0
0
50
0
0
0
0
0
0
13
0
% D
% Glu:
0
13
0
13
0
13
25
0
0
75
0
0
0
13
0
% E
% Phe:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
13
0
0
0
0
13
0
13
25
13
0
0
0
% H
% Ile:
75
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
0
0
0
0
0
75
0
% K
% Leu:
0
0
0
0
13
0
13
0
0
0
13
13
0
0
0
% L
% Met:
0
0
0
0
0
0
0
13
0
0
0
75
13
0
0
% M
% Asn:
0
0
63
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
75
0
0
0
13
13
0
0
0
0
0
0
0
13
% P
% Gln:
0
0
0
0
75
0
0
0
13
0
0
0
13
0
13
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
13
0
0
13
0
38
0
13
50
0
0
0
13
% S
% Thr:
0
13
0
0
0
63
0
13
0
0
0
0
13
0
38
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _