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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX35
All Species:
17.88
Human Site:
S28
Identified Species:
28.1
UniProt:
Q9H5Z1
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H5Z1
NP_068750.2
703
78910
S28
S
I
S
E
E
R
Q
S
L
A
E
N
S
G
T
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
L99
E
K
N
R
S
Y
R
L
L
E
D
S
E
E
S
Rhesus Macaque
Macaca mulatta
XP_001088680
703
78826
S28
S
I
S
E
E
R
Q
S
L
T
E
N
S
G
T
Dog
Lupus familis
XP_542996
769
85800
S28
S
I
S
E
E
R
Q
S
L
A
E
N
S
A
T
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
T91
N
L
L
R
L
I
Q
T
M
R
P
P
A
K
P
Rat
Rattus norvegicus
Q5XI69
779
88496
V22
Q
E
E
G
E
R
P
V
E
L
Q
E
E
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512863
703
79017
S28
S
I
S
E
E
R
Q
S
A
A
E
C
T
E
T
Chicken
Gallus gallus
XP_417352
703
78661
S28
S
V
S
E
E
R
Q
S
P
A
E
S
S
G
V
Frog
Xenopus laevis
Q5XH12
748
85094
E36
S
S
D
V
E
G
D
E
L
N
D
L
E
L
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396598
671
75928
A21
S
T
Q
F
V
Y
N
A
Y
H
S
L
A
L
N
Nematode Worm
Caenorhab. elegans
Q9BKQ8
732
82525
A51
S
T
E
N
A
G
A
A
P
P
I
E
E
Q
L
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
XP_002305762
702
78145
V23
L
E
D
E
E
G
G
V
V
F
F
G
P
P
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
E439
A
L
T
K
E
R
R
E
M
R
E
Q
Q
Q
R
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
L91
V
L
K
D
D
V
N
L
D
D
P
V
V
T
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.6
98.2
88.1
N.A.
26.5
34.4
N.A.
90.9
90
27.8
N.A.
N.A.
N.A.
53.6
51.3
32.4
Protein Similarity:
100
44.1
99
89.8
N.A.
39
53.4
N.A.
96.7
95.8
49
N.A.
N.A.
N.A.
72.5
70.9
46.6
P-Site Identity:
100
6.6
93.3
93.3
N.A.
6.6
13.3
N.A.
73.3
73.3
20
N.A.
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
100
40
93.3
93.3
N.A.
40
20
N.A.
80
86.6
26.6
N.A.
N.A.
N.A.
20
13.3
0
Percent
Protein Identity:
49
N.A.
N.A.
25.8
28.2
N.A.
Protein Similarity:
68.2
N.A.
N.A.
39.9
42
N.A.
P-Site Identity:
13.3
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
60
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
7
14
7
27
0
0
14
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
14
7
7
0
7
0
7
7
14
0
0
0
0
% D
% Glu:
7
14
14
40
60
0
0
14
7
7
40
14
27
14
7
% E
% Phe:
0
0
0
7
0
0
0
0
0
7
7
0
0
0
0
% F
% Gly:
0
0
0
7
0
20
7
0
0
0
0
7
0
20
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
27
0
0
0
7
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
7
7
7
0
0
0
0
0
0
0
0
0
7
0
% K
% Leu:
7
20
7
0
7
0
0
14
34
7
0
14
0
14
14
% L
% Met:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% M
% Asn:
7
0
7
7
0
0
14
0
0
7
0
20
0
0
14
% N
% Pro:
0
0
0
0
0
0
7
0
14
7
14
7
7
7
14
% P
% Gln:
7
0
7
0
0
0
40
0
0
0
7
7
7
14
0
% Q
% Arg:
0
0
0
14
0
47
14
0
0
14
0
0
0
7
7
% R
% Ser:
54
7
34
0
7
0
0
34
0
0
7
14
27
0
7
% S
% Thr:
0
14
7
0
0
0
0
7
0
7
0
0
7
7
27
% T
% Val:
7
7
0
7
7
7
0
14
7
0
0
7
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
14
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _