KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX35
All Species:
19.09
Human Site:
S417
Identified Species:
30
UniProt:
Q9H5Z1
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H5Z1
NP_068750.2
703
78910
S417
A
F
D
K
L
P
Q
S
T
V
P
E
M
Q
R
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
E752
A
Y
Q
H
E
L
E
E
T
T
V
P
E
I
Q
Rhesus Macaque
Macaca mulatta
XP_001088680
703
78826
S417
A
F
D
K
L
P
Q
S
T
V
P
E
M
Q
R
Dog
Lupus familis
XP_542996
769
85800
C417
A
F
D
K
L
P
Q
C
T
V
P
E
M
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
T938
A
Y
R
D
E
M
L
T
T
N
V
P
E
I
Q
Rat
Rattus norvegicus
Q5XI69
779
88496
D420
F
W
N
Q
C
M
P
D
H
V
I
P
E
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512863
703
79017
S417
D
F
D
K
L
P
Q
S
T
V
P
E
M
Q
R
Chicken
Gallus gallus
XP_417352
703
78661
S417
D
F
E
K
L
P
Q
S
T
V
P
E
M
Q
R
Frog
Xenopus laevis
Q5XH12
748
85094
N427
T
A
K
V
E
E
C
N
L
I
S
M
V
L
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396598
671
75928
T394
A
Y
S
E
L
F
E
T
T
P
P
E
M
Q
R
Nematode Worm
Caenorhab. elegans
Q9BKQ8
732
82525
P439
R
F
A
E
G
T
V
P
E
I
Q
R
C
Q
M
Sea Urchin
Strong. purpuratus
O17438
455
51461
G200
E
T
S
L
T
I
D
G
V
V
F
V
I
D
P
Poplar Tree
Populus trichocarpa
XP_002305762
702
78145
S420
Y
F
V
N
E
M
S
S
V
G
I
P
E
M
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
P864
A
Y
R
N
E
M
P
P
T
S
I
P
E
I
Q
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
E832
A
F
Y
N
E
M
L
E
N
T
V
P
E
I
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.6
98.2
88.1
N.A.
26.5
34.4
N.A.
90.9
90
27.8
N.A.
N.A.
N.A.
53.6
51.3
32.4
Protein Similarity:
100
44.1
99
89.8
N.A.
39
53.4
N.A.
96.7
95.8
49
N.A.
N.A.
N.A.
72.5
70.9
46.6
P-Site Identity:
100
13.3
100
93.3
N.A.
13.3
6.6
N.A.
93.3
86.6
0
N.A.
N.A.
N.A.
53.3
13.3
6.6
P-Site Similarity:
100
33.3
100
93.3
N.A.
33.3
33.3
N.A.
93.3
93.3
20
N.A.
N.A.
N.A.
80
26.6
13.3
Percent
Protein Identity:
49
N.A.
N.A.
25.8
28.2
N.A.
Protein Similarity:
68.2
N.A.
N.A.
39.9
42
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
7
0
7
7
0
0
0
0
7
0
0
% C
% Asp:
14
0
27
7
0
0
7
7
0
0
0
0
0
7
0
% D
% Glu:
7
0
7
14
40
7
14
14
7
0
0
40
40
0
0
% E
% Phe:
7
54
0
0
0
7
0
0
0
0
7
0
0
0
7
% F
% Gly:
0
0
0
0
7
0
0
7
0
7
0
0
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
0
14
20
0
7
34
0
% I
% Lys:
0
0
7
34
0
0
0
0
0
0
0
0
0
0
7
% K
% Leu:
0
0
0
7
40
7
14
0
7
0
0
0
0
7
0
% L
% Met:
0
0
0
0
0
34
0
0
0
0
0
7
40
7
7
% M
% Asn:
0
0
7
20
0
0
0
7
7
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
34
14
14
0
7
40
40
0
0
7
% P
% Gln:
0
0
7
7
0
0
34
0
0
0
7
0
0
47
34
% Q
% Arg:
7
0
14
0
0
0
0
0
0
0
0
7
0
0
40
% R
% Ser:
0
0
14
0
0
0
7
34
0
7
7
0
0
0
0
% S
% Thr:
7
7
0
0
7
7
0
14
60
14
0
0
0
0
0
% T
% Val:
0
0
7
7
0
0
7
0
14
47
20
7
7
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
27
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _