KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX35
All Species:
26.67
Human Site:
S449
Identified Species:
41.9
UniProt:
Q9H5Z1
Number Species:
14
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H5Z1
NP_068750.2
703
78910
S449
V
L
R
F
H
F
M
S
P
P
P
A
Q
S
M
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
D785
L
M
H
F
D
F
L
D
P
P
P
Y
E
T
L
Rhesus Macaque
Macaca mulatta
XP_001088680
703
78826
S449
V
L
R
F
H
F
M
S
P
P
P
A
Q
S
M
Dog
Lupus familis
XP_542996
769
85800
S449
V
L
R
F
H
F
M
S
P
P
P
A
Q
S
M
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
D971
L
L
S
F
D
F
M
D
A
P
P
M
E
T
L
Rat
Rattus norvegicus
Q5XI69
779
88496
D453
V
I
R
F
P
Y
L
D
P
P
N
E
R
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512863
703
79017
S449
V
L
R
F
H
F
M
S
P
P
P
A
Q
S
M
Chicken
Gallus gallus
XP_417352
703
78661
S449
V
L
R
F
P
F
L
S
P
P
P
A
Q
S
M
Frog
Xenopus laevis
Q5XH12
748
85094
N450
L
A
H
C
D
F
I
N
R
P
D
P
E
S
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396598
671
75928
S426
V
L
R
F
N
F
P
S
A
P
P
S
K
N
L
Nematode Worm
Caenorhab. elegans
Q9BKQ8
732
82525
S468
V
H
R
F
H
Y
L
S
P
P
P
S
W
A
M
Sea Urchin
Strong. purpuratus
O17438
455
51461
S223
N
P
R
I
R
V
E
S
L
L
V
S
P
I
S
Poplar Tree
Populus trichocarpa
XP_002305762
702
78145
A453
I
L
G
F
D
W
P
A
S
P
P
P
E
A
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
D897
L
L
S
F
D
F
M
D
P
P
Q
P
Q
A
L
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
D865
L
L
K
F
D
F
M
D
P
P
P
K
N
L
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.6
98.2
88.1
N.A.
26.5
34.4
N.A.
90.9
90
27.8
N.A.
N.A.
N.A.
53.6
51.3
32.4
Protein Similarity:
100
44.1
99
89.8
N.A.
39
53.4
N.A.
96.7
95.8
49
N.A.
N.A.
N.A.
72.5
70.9
46.6
P-Site Identity:
100
33.3
100
100
N.A.
40
33.3
N.A.
100
86.6
20
N.A.
N.A.
N.A.
53.3
60
13.3
P-Site Similarity:
100
73.3
100
100
N.A.
66.6
66.6
N.A.
100
93.3
53.3
N.A.
N.A.
N.A.
86.6
86.6
20
Percent
Protein Identity:
49
N.A.
N.A.
25.8
28.2
N.A.
Protein Similarity:
68.2
N.A.
N.A.
39.9
42
N.A.
P-Site Identity:
33.3
N.A.
N.A.
46.6
53.3
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
66.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
7
14
0
0
34
0
20
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
40
0
0
34
0
0
7
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
7
0
0
0
0
7
27
0
0
% E
% Phe:
0
0
0
87
0
74
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
14
0
34
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
7
0
7
0
0
7
0
0
0
0
0
0
7
7
% I
% Lys:
0
0
7
0
0
0
0
0
0
0
0
7
7
0
0
% K
% Leu:
34
67
0
0
0
0
27
0
7
7
0
0
0
14
34
% L
% Met:
0
7
0
0
0
0
47
0
0
0
0
7
0
0
54
% M
% Asn:
7
0
0
0
7
0
0
7
0
0
7
0
7
7
0
% N
% Pro:
0
7
0
0
14
0
14
0
67
94
74
20
7
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
40
0
0
% Q
% Arg:
0
0
60
0
7
0
0
0
7
0
0
0
7
0
0
% R
% Ser:
0
0
14
0
0
0
0
54
7
0
0
20
0
40
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% T
% Val:
54
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
14
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _