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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX35 All Species: 26.67
Human Site: S449 Identified Species: 41.9
UniProt: Q9H5Z1 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H5Z1 NP_068750.2 703 78910 S449 V L R F H F M S P P P A Q S M
Chimpanzee Pan troglodytes Q7YR39 1044 119631 D785 L M H F D F L D P P P Y E T L
Rhesus Macaque Macaca mulatta XP_001088680 703 78826 S449 V L R F H F M S P P P A Q S M
Dog Lupus familis XP_542996 769 85800 S449 V L R F H F M S P P P A Q S M
Cat Felis silvestris
Mouse Mus musculus A2A4P0 1244 142553 D971 L L S F D F M D A P P M E T L
Rat Rattus norvegicus Q5XI69 779 88496 D453 V I R F P Y L D P P N E R L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512863 703 79017 S449 V L R F H F M S P P P A Q S M
Chicken Gallus gallus XP_417352 703 78661 S449 V L R F P F L S P P P A Q S M
Frog Xenopus laevis Q5XH12 748 85094 N450 L A H C D F I N R P D P E S L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396598 671 75928 S426 V L R F N F P S A P P S K N L
Nematode Worm Caenorhab. elegans Q9BKQ8 732 82525 S468 V H R F H Y L S P P P S W A M
Sea Urchin Strong. purpuratus O17438 455 51461 S223 N P R I R V E S L L V S P I S
Poplar Tree Populus trichocarpa XP_002305762 702 78145 A453 I L G F D W P A S P P P E A M
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 D897 L L S F D F M D P P Q P Q A L
Baker's Yeast Sacchar. cerevisiae P24384 1145 129992 D865 L L K F D F M D P P P K N L M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 29.6 98.2 88.1 N.A. 26.5 34.4 N.A. 90.9 90 27.8 N.A. N.A. N.A. 53.6 51.3 32.4
Protein Similarity: 100 44.1 99 89.8 N.A. 39 53.4 N.A. 96.7 95.8 49 N.A. N.A. N.A. 72.5 70.9 46.6
P-Site Identity: 100 33.3 100 100 N.A. 40 33.3 N.A. 100 86.6 20 N.A. N.A. N.A. 53.3 60 13.3
P-Site Similarity: 100 73.3 100 100 N.A. 66.6 66.6 N.A. 100 93.3 53.3 N.A. N.A. N.A. 86.6 86.6 20
Percent
Protein Identity: 49 N.A. N.A. 25.8 28.2 N.A.
Protein Similarity: 68.2 N.A. N.A. 39.9 42 N.A.
P-Site Identity: 33.3 N.A. N.A. 46.6 53.3 N.A.
P-Site Similarity: 66.6 N.A. N.A. 66.6 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 7 14 0 0 34 0 20 0 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 40 0 0 34 0 0 7 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 7 0 0 0 0 7 27 0 0 % E
% Phe: 0 0 0 87 0 74 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 7 14 0 34 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 7 0 7 0 0 7 0 0 0 0 0 0 7 7 % I
% Lys: 0 0 7 0 0 0 0 0 0 0 0 7 7 0 0 % K
% Leu: 34 67 0 0 0 0 27 0 7 7 0 0 0 14 34 % L
% Met: 0 7 0 0 0 0 47 0 0 0 0 7 0 0 54 % M
% Asn: 7 0 0 0 7 0 0 7 0 0 7 0 7 7 0 % N
% Pro: 0 7 0 0 14 0 14 0 67 94 74 20 7 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 7 0 40 0 0 % Q
% Arg: 0 0 60 0 7 0 0 0 7 0 0 0 7 0 0 % R
% Ser: 0 0 14 0 0 0 0 54 7 0 0 20 0 40 7 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 14 0 % T
% Val: 54 0 0 0 0 7 0 0 0 0 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 0 0 0 0 14 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _