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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX35
All Species:
11.82
Human Site:
S529
Identified Species:
18.57
UniProt:
Q9H5Z1
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H5Z1
NP_068750.2
703
78910
S529
V
V
P
P
N
Q
K
S
H
A
I
R
V
H
R
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
V865
Y
R
P
K
D
K
V
V
H
A
D
N
A
R
V
Rhesus Macaque
Macaca mulatta
XP_001088680
703
78826
S529
V
V
P
P
N
Q
K
S
Q
A
I
R
V
H
R
Dog
Lupus familis
XP_542996
769
85800
S529
V
V
P
G
N
Q
K
S
Q
A
I
R
V
H
R
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
A1050
Y
R
P
K
D
K
Q
A
L
A
D
Q
K
K
A
Rat
Rattus norvegicus
Q5XI69
779
88496
K534
P
V
D
P
E
Y
Q
K
E
A
E
Q
K
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512863
703
79017
A529
V
I
P
P
N
Q
K
A
Q
A
I
R
Q
H
R
Chicken
Gallus gallus
XP_417352
703
78661
S529
L
I
P
P
N
Q
K
S
Q
A
A
R
Q
H
R
Frog
Xenopus laevis
Q5XH12
748
85094
L531
L
P
P
E
A
K
E
L
D
L
I
G
K
G
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396598
671
75928
Q505
F
I
R
P
A
G
G
Q
A
A
I
K
A
R
I
Nematode Worm
Caenorhab. elegans
Q9BKQ8
732
82525
H548
I
T
P
Y
R
Q
R
H
Q
A
D
V
I
R
K
Sea Urchin
Strong. purpuratus
O17438
455
51461
V291
K
L
G
I
D
D
L
V
H
F
D
F
M
D
P
Poplar Tree
Populus trichocarpa
XP_002305762
702
78145
L535
G
R
G
V
Q
K
E
L
D
E
A
K
L
R
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
A976
Y
R
P
R
E
K
Q
A
Q
A
D
Q
K
R
A
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
L944
Y
R
P
K
D
R
Q
L
E
A
D
S
K
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.6
98.2
88.1
N.A.
26.5
34.4
N.A.
90.9
90
27.8
N.A.
N.A.
N.A.
53.6
51.3
32.4
Protein Similarity:
100
44.1
99
89.8
N.A.
39
53.4
N.A.
96.7
95.8
49
N.A.
N.A.
N.A.
72.5
70.9
46.6
P-Site Identity:
100
20
93.3
86.6
N.A.
13.3
33.3
N.A.
73.3
66.6
13.3
N.A.
N.A.
N.A.
20
20
6.6
P-Site Similarity:
100
33.3
93.3
86.6
N.A.
46.6
46.6
N.A.
86.6
80
40
N.A.
N.A.
N.A.
33.3
46.6
26.6
Percent
Protein Identity:
49
N.A.
N.A.
25.8
28.2
N.A.
Protein Similarity:
68.2
N.A.
N.A.
39.9
42
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
14
0
0
20
7
80
14
0
14
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
27
7
0
0
14
0
40
0
0
7
0
% D
% Glu:
0
0
0
7
14
0
14
0
14
7
7
0
0
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
7
0
7
0
0
7
% F
% Gly:
7
0
14
7
0
7
7
0
0
0
0
7
0
7
0
% G
% His:
0
0
0
0
0
0
0
7
20
0
0
0
0
40
0
% H
% Ile:
7
20
0
7
0
0
0
0
0
0
40
0
7
0
7
% I
% Lys:
7
0
0
20
0
34
34
7
0
0
0
14
34
14
14
% K
% Leu:
14
7
0
0
0
0
7
20
7
7
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
34
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
7
7
74
40
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
7
40
27
7
40
0
0
20
14
0
0
% Q
% Arg:
0
34
7
7
7
7
7
0
0
0
0
34
0
34
40
% R
% Ser:
0
0
0
0
0
0
0
27
0
0
0
7
0
0
0
% S
% Thr:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
27
27
0
7
0
0
7
14
0
0
0
7
20
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
27
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _