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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX35 All Species: 11.82
Human Site: S529 Identified Species: 18.57
UniProt: Q9H5Z1 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H5Z1 NP_068750.2 703 78910 S529 V V P P N Q K S H A I R V H R
Chimpanzee Pan troglodytes Q7YR39 1044 119631 V865 Y R P K D K V V H A D N A R V
Rhesus Macaque Macaca mulatta XP_001088680 703 78826 S529 V V P P N Q K S Q A I R V H R
Dog Lupus familis XP_542996 769 85800 S529 V V P G N Q K S Q A I R V H R
Cat Felis silvestris
Mouse Mus musculus A2A4P0 1244 142553 A1050 Y R P K D K Q A L A D Q K K A
Rat Rattus norvegicus Q5XI69 779 88496 K534 P V D P E Y Q K E A E Q K H R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512863 703 79017 A529 V I P P N Q K A Q A I R Q H R
Chicken Gallus gallus XP_417352 703 78661 S529 L I P P N Q K S Q A A R Q H R
Frog Xenopus laevis Q5XH12 748 85094 L531 L P P E A K E L D L I G K G K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396598 671 75928 Q505 F I R P A G G Q A A I K A R I
Nematode Worm Caenorhab. elegans Q9BKQ8 732 82525 H548 I T P Y R Q R H Q A D V I R K
Sea Urchin Strong. purpuratus O17438 455 51461 V291 K L G I D D L V H F D F M D P
Poplar Tree Populus trichocarpa XP_002305762 702 78145 L535 G R G V Q K E L D E A K L R F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 A976 Y R P R E K Q A Q A D Q K R A
Baker's Yeast Sacchar. cerevisiae P24384 1145 129992 L944 Y R P K D R Q L E A D S K K A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 29.6 98.2 88.1 N.A. 26.5 34.4 N.A. 90.9 90 27.8 N.A. N.A. N.A. 53.6 51.3 32.4
Protein Similarity: 100 44.1 99 89.8 N.A. 39 53.4 N.A. 96.7 95.8 49 N.A. N.A. N.A. 72.5 70.9 46.6
P-Site Identity: 100 20 93.3 86.6 N.A. 13.3 33.3 N.A. 73.3 66.6 13.3 N.A. N.A. N.A. 20 20 6.6
P-Site Similarity: 100 33.3 93.3 86.6 N.A. 46.6 46.6 N.A. 86.6 80 40 N.A. N.A. N.A. 33.3 46.6 26.6
Percent
Protein Identity: 49 N.A. N.A. 25.8 28.2 N.A.
Protein Similarity: 68.2 N.A. N.A. 39.9 42 N.A.
P-Site Identity: 0 N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: 26.6 N.A. N.A. 40 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 14 0 0 20 7 80 14 0 14 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 27 7 0 0 14 0 40 0 0 7 0 % D
% Glu: 0 0 0 7 14 0 14 0 14 7 7 0 0 0 0 % E
% Phe: 7 0 0 0 0 0 0 0 0 7 0 7 0 0 7 % F
% Gly: 7 0 14 7 0 7 7 0 0 0 0 7 0 7 0 % G
% His: 0 0 0 0 0 0 0 7 20 0 0 0 0 40 0 % H
% Ile: 7 20 0 7 0 0 0 0 0 0 40 0 7 0 7 % I
% Lys: 7 0 0 20 0 34 34 7 0 0 0 14 34 14 14 % K
% Leu: 14 7 0 0 0 0 7 20 7 7 0 0 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 0 0 0 34 0 0 0 0 0 0 7 0 0 0 % N
% Pro: 7 7 74 40 0 0 0 0 0 0 0 0 0 0 7 % P
% Gln: 0 0 0 0 7 40 27 7 40 0 0 20 14 0 0 % Q
% Arg: 0 34 7 7 7 7 7 0 0 0 0 34 0 34 40 % R
% Ser: 0 0 0 0 0 0 0 27 0 0 0 7 0 0 0 % S
% Thr: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 27 27 0 7 0 0 7 14 0 0 0 7 20 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 27 0 0 7 0 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _