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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX35
All Species:
20.91
Human Site:
S598
Identified Species:
32.86
UniProt:
Q9H5Z1
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H5Z1
NP_068750.2
703
78910
S598
K
F
Q
V
P
R
K
S
S
E
G
D
P
D
L
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
L932
L
E
R
V
E
V
G
L
S
S
C
Q
G
D
Y
Rhesus Macaque
Macaca mulatta
XP_001088680
703
78826
S598
K
F
Q
V
P
K
K
S
S
E
G
D
P
D
P
Dog
Lupus familis
XP_542996
769
85800
S598
K
F
Q
V
P
K
K
S
S
E
G
D
P
D
P
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
V1118
D
R
H
K
L
D
V
V
S
C
G
K
S
T
V
Rat
Rattus norvegicus
Q5XI69
779
88496
G613
F
P
R
E
T
F
E
G
P
K
H
E
V
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512863
703
79017
S598
K
F
K
V
P
K
K
S
S
E
G
D
P
D
P
Chicken
Gallus gallus
XP_417352
703
78661
S598
C
F
K
V
P
K
K
S
S
E
G
D
P
D
P
Frog
Xenopus laevis
Q5XH12
748
85094
G610
P
L
T
G
P
A
F
G
S
D
E
N
V
T
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396598
671
75928
L570
M
H
S
M
M
K
K
L
N
I
P
L
V
S
C
Nematode Worm
Caenorhab. elegans
Q9BKQ8
732
82525
G620
I
E
K
V
S
S
R
G
L
I
N
C
S
E
N
Sea Urchin
Strong. purpuratus
O17438
455
51461
E354
T
D
Y
S
C
S
N
E
I
L
S
V
T
A
M
Poplar Tree
Populus trichocarpa
XP_002305762
702
78145
K601
L
R
L
G
I
V
L
K
S
C
E
G
D
M
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
T1045
K
Y
K
L
D
V
V
T
A
G
K
N
F
T
K
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
S1013
K
I
G
L
K
L
I
S
C
H
S
D
P
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.6
98.2
88.1
N.A.
26.5
34.4
N.A.
90.9
90
27.8
N.A.
N.A.
N.A.
53.6
51.3
32.4
Protein Similarity:
100
44.1
99
89.8
N.A.
39
53.4
N.A.
96.7
95.8
49
N.A.
N.A.
N.A.
72.5
70.9
46.6
P-Site Identity:
100
20
86.6
86.6
N.A.
13.3
0
N.A.
80
73.3
13.3
N.A.
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
100
26.6
93.3
93.3
N.A.
20
26.6
N.A.
93.3
86.6
26.6
N.A.
N.A.
N.A.
26.6
26.6
6.6
Percent
Protein Identity:
49
N.A.
N.A.
25.8
28.2
N.A.
Protein Similarity:
68.2
N.A.
N.A.
39.9
42
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
40
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
46.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
7
0
0
0
0
7
0
% A
% Cys:
7
0
0
0
7
0
0
0
7
14
7
7
0
0
7
% C
% Asp:
7
7
0
0
7
7
0
0
0
7
0
40
7
47
0
% D
% Glu:
0
14
0
7
7
0
7
7
0
34
14
7
0
7
0
% E
% Phe:
7
34
0
0
0
7
7
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
7
14
0
0
7
20
0
7
40
7
7
0
0
% G
% His:
0
7
7
0
0
0
0
0
0
7
7
0
0
0
0
% H
% Ile:
7
7
0
0
7
0
7
0
7
14
0
0
0
0
0
% I
% Lys:
40
0
27
7
7
34
40
7
0
7
7
7
0
0
7
% K
% Leu:
14
7
7
14
7
7
7
14
7
7
0
7
0
7
20
% L
% Met:
7
0
0
7
7
0
0
0
0
0
0
0
0
7
7
% M
% Asn:
0
0
0
0
0
0
7
0
7
0
7
14
0
0
14
% N
% Pro:
7
7
0
0
40
0
0
0
7
0
7
0
40
0
27
% P
% Gln:
0
0
20
0
0
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
14
14
0
0
7
7
0
0
0
0
0
0
0
7
% R
% Ser:
0
0
7
7
7
14
0
40
60
7
14
0
14
7
0
% S
% Thr:
7
0
7
0
7
0
0
7
0
0
0
0
7
20
0
% T
% Val:
0
0
0
47
0
20
14
7
0
0
0
7
20
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _