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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX35 All Species: 21.52
Human Site: S599 Identified Species: 33.81
UniProt: Q9H5Z1 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H5Z1 NP_068750.2 703 78910 S599 F Q V P R K S S E G D P D L V
Chimpanzee Pan troglodytes Q7YR39 1044 119631 S933 E R V E V G L S S C Q G D Y I
Rhesus Macaque Macaca mulatta XP_001088680 703 78826 S599 F Q V P K K S S E G D P D P V
Dog Lupus familis XP_542996 769 85800 S599 F Q V P K K S S E G D P D P V
Cat Felis silvestris
Mouse Mus musculus A2A4P0 1244 142553 S1119 R H K L D V V S C G K S T V R
Rat Rattus norvegicus Q5XI69 779 88496 P614 P R E T F E G P K H E V L R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512863 703 79017 S599 F K V P K K S S E G D P D P V
Chicken Gallus gallus XP_417352 703 78661 S599 F K V P K K S S E G D P D P V
Frog Xenopus laevis Q5XH12 748 85094 S611 L T G P A F G S D E N V T N I
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396598 671 75928 N571 H S M M K K L N I P L V S C N
Nematode Worm Caenorhab. elegans Q9BKQ8 732 82525 L621 E K V S S R G L I N C S E N I
Sea Urchin Strong. purpuratus O17438 455 51461 I355 D Y S C S N E I L S V T A M L
Poplar Tree Populus trichocarpa XP_002305762 702 78145 S602 R L G I V L K S C E G D M L A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 A1046 Y K L D V V T A G K N F T K I
Baker's Yeast Sacchar. cerevisiae P24384 1145 129992 C1014 I G L K L I S C H S D P D L I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 29.6 98.2 88.1 N.A. 26.5 34.4 N.A. 90.9 90 27.8 N.A. N.A. N.A. 53.6 51.3 32.4
Protein Similarity: 100 44.1 99 89.8 N.A. 39 53.4 N.A. 96.7 95.8 49 N.A. N.A. N.A. 72.5 70.9 46.6
P-Site Identity: 100 20 86.6 86.6 N.A. 13.3 0 N.A. 80 80 13.3 N.A. N.A. N.A. 6.6 6.6 0
P-Site Similarity: 100 33.3 93.3 93.3 N.A. 20 26.6 N.A. 93.3 93.3 33.3 N.A. N.A. N.A. 26.6 33.3 13.3
Percent
Protein Identity: 49 N.A. N.A. 25.8 28.2 N.A.
Protein Similarity: 68.2 N.A. N.A. 39.9 42 N.A.
P-Site Identity: 13.3 N.A. N.A. 0 33.3 N.A.
P-Site Similarity: 13.3 N.A. N.A. 46.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 0 7 0 0 0 0 7 0 7 % A
% Cys: 0 0 0 7 0 0 0 7 14 7 7 0 0 7 0 % C
% Asp: 7 0 0 7 7 0 0 0 7 0 40 7 47 0 0 % D
% Glu: 14 0 7 7 0 7 7 0 34 14 7 0 7 0 0 % E
% Phe: 34 0 0 0 7 7 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 7 14 0 0 7 20 0 7 40 7 7 0 0 0 % G
% His: 7 7 0 0 0 0 0 0 7 7 0 0 0 0 0 % H
% Ile: 7 0 0 7 0 7 0 7 14 0 0 0 0 0 34 % I
% Lys: 0 27 7 7 34 40 7 0 7 7 7 0 0 7 0 % K
% Leu: 7 7 14 7 7 7 14 7 7 0 7 0 7 20 7 % L
% Met: 0 0 7 7 0 0 0 0 0 0 0 0 7 7 0 % M
% Asn: 0 0 0 0 0 7 0 7 0 7 14 0 0 14 7 % N
% Pro: 7 0 0 40 0 0 0 7 0 7 0 40 0 27 0 % P
% Gln: 0 20 0 0 0 0 0 0 0 0 7 0 0 0 0 % Q
% Arg: 14 14 0 0 7 7 0 0 0 0 0 0 0 7 14 % R
% Ser: 0 7 7 7 14 0 40 60 7 14 0 14 7 0 0 % S
% Thr: 0 7 0 7 0 0 7 0 0 0 0 7 20 0 0 % T
% Val: 0 0 47 0 20 14 7 0 0 0 7 20 0 7 34 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 7 0 0 0 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _