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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX35 All Species: 13.64
Human Site: T35 Identified Species: 21.43
UniProt: Q9H5Z1 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H5Z1 NP_068750.2 703 78910 T35 S L A E N S G T T V V Y N P Y
Chimpanzee Pan troglodytes Q7YR39 1044 119631 S106 L L E D S E E S S E E T V S R
Rhesus Macaque Macaca mulatta XP_001088680 703 78826 T35 S L T E N S G T T V V Y N P Y
Dog Lupus familis XP_542996 769 85800 T35 S L A E N S A T T V V Y N P Y
Cat Felis silvestris
Mouse Mus musculus A2A4P0 1244 142553 P98 T M R P P A K P S T S K D P V
Rat Rattus norvegicus Q5XI69 779 88496 P29 V E L Q E E R P S A V R I A D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512863 703 79017 T35 S A A E C T E T T V I Y N P H
Chicken Gallus gallus XP_417352 703 78661 V35 S P A E S S G V T V V Y N P Y
Frog Xenopus laevis Q5XH12 748 85094 N43 E L N D L E L N P F D G L P Y
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396598 671 75928 N28 A Y H S L A L N M Q R Q R L P
Nematode Worm Caenorhab. elegans Q9BKQ8 732 82525 L58 A P P I E E Q L K V H N N P Y
Sea Urchin Strong. purpuratus O17438 455 51461
Poplar Tree Populus trichocarpa XP_002305762 702 78145 L30 V V F F G P P L S S A A S S S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 R446 E M R E Q Q Q R T M L D S I P
Baker's Yeast Sacchar. cerevisiae P24384 1145 129992 E98 L D D P V V T E F V L S I L N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 29.6 98.2 88.1 N.A. 26.5 34.4 N.A. 90.9 90 27.8 N.A. N.A. N.A. 53.6 51.3 32.4
Protein Similarity: 100 44.1 99 89.8 N.A. 39 53.4 N.A. 96.7 95.8 49 N.A. N.A. N.A. 72.5 70.9 46.6
P-Site Identity: 100 6.6 93.3 93.3 N.A. 6.6 6.6 N.A. 60 80 20 N.A. N.A. N.A. 0 26.6 0
P-Site Similarity: 100 33.3 93.3 93.3 N.A. 40 20 N.A. 80 86.6 26.6 N.A. N.A. N.A. 13.3 33.3 0
Percent
Protein Identity: 49 N.A. N.A. 25.8 28.2 N.A.
Protein Similarity: 68.2 N.A. N.A. 39.9 42 N.A.
P-Site Identity: 0 N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 20 N.A. N.A. 40 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 27 0 0 14 7 0 0 7 7 7 0 7 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 14 0 0 0 0 0 0 7 7 7 0 7 % D
% Glu: 14 7 7 40 14 27 14 7 0 7 7 0 0 0 0 % E
% Phe: 0 0 7 7 0 0 0 0 7 7 0 0 0 0 0 % F
% Gly: 0 0 0 0 7 0 20 0 0 0 0 7 0 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 7 0 0 0 7 % H
% Ile: 0 0 0 7 0 0 0 0 0 0 7 0 14 7 0 % I
% Lys: 0 0 0 0 0 0 7 0 7 0 0 7 0 0 0 % K
% Leu: 14 34 7 0 14 0 14 14 0 0 14 0 7 14 0 % L
% Met: 0 14 0 0 0 0 0 0 7 7 0 0 0 0 0 % M
% Asn: 0 0 7 0 20 0 0 14 0 0 0 7 40 0 7 % N
% Pro: 0 14 7 14 7 7 7 14 7 0 0 0 0 54 14 % P
% Gln: 0 0 0 7 7 7 14 0 0 7 0 7 0 0 0 % Q
% Arg: 0 0 14 0 0 0 7 7 0 0 7 7 7 0 7 % R
% Ser: 34 0 0 7 14 27 0 7 27 7 7 7 14 14 7 % S
% Thr: 7 0 7 0 0 7 7 27 40 7 0 7 0 0 0 % T
% Val: 14 7 0 0 7 7 0 7 0 47 34 0 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 0 0 0 0 34 0 0 40 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _