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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX35
All Species:
13.33
Human Site:
T580
Identified Species:
20.95
UniProt:
Q9H5Z1
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H5Z1
NP_068750.2
703
78910
T580
K
G
L
V
R
A
A
T
V
R
E
Q
L
K
K
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
D916
R
S
M
R
R
A
R
D
V
R
E
Q
L
E
G
Rhesus Macaque
Macaca mulatta
XP_001088680
703
78826
T580
K
G
L
V
R
A
A
T
V
R
E
Q
L
K
K
Dog
Lupus familis
XP_542996
769
85800
T580
K
G
L
I
R
A
A
T
V
R
E
Q
L
K
K
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
D1101
R
S
L
R
R
A
Q
D
I
R
K
Q
M
L
G
Rat
Rattus norvegicus
Q5XI69
779
88496
R588
R
C
L
F
S
A
F
R
V
E
A
Q
L
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512863
703
79017
T580
K
G
L
V
R
A
T
T
V
R
E
Q
L
K
K
Chicken
Gallus gallus
XP_417352
703
78661
V580
K
G
L
V
R
A
S
V
V
R
E
Q
L
K
K
Frog
Xenopus laevis
Q5XH12
748
85094
V581
Q
N
H
C
L
S
F
V
A
L
E
M
A
R
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396598
671
75928
L553
Q
F
L
N
N
K
A
L
R
R
A
M
E
I
R
Nematode Worm
Caenorhab. elegans
Q9BKQ8
732
82525
N599
R
G
L
M
R
A
D
N
V
R
S
Q
L
V
R
Sea Urchin
Strong. purpuratus
O17438
455
51461
L339
E
F
P
L
D
P
Q
L
A
K
M
V
I
A
S
Poplar Tree
Populus trichocarpa
XP_002305762
702
78145
E584
Q
A
M
K
K
V
I
E
I
R
E
Q
L
R
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
D1027
R
S
L
R
R
A
Q
D
V
R
K
Q
L
L
S
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
D995
R
H
L
K
R
A
R
D
V
K
S
Q
I
S
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.6
98.2
88.1
N.A.
26.5
34.4
N.A.
90.9
90
27.8
N.A.
N.A.
N.A.
53.6
51.3
32.4
Protein Similarity:
100
44.1
99
89.8
N.A.
39
53.4
N.A.
96.7
95.8
49
N.A.
N.A.
N.A.
72.5
70.9
46.6
P-Site Identity:
100
46.6
100
93.3
N.A.
33.3
33.3
N.A.
93.3
86.6
6.6
N.A.
N.A.
N.A.
20
53.3
0
P-Site Similarity:
100
66.6
100
100
N.A.
60
53.3
N.A.
93.3
93.3
26.6
N.A.
N.A.
N.A.
33.3
73.3
26.6
Percent
Protein Identity:
49
N.A.
N.A.
25.8
28.2
N.A.
Protein Similarity:
68.2
N.A.
N.A.
39.9
42
N.A.
P-Site Identity:
26.6
N.A.
N.A.
46.6
33.3
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
60
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
74
27
0
14
0
14
0
7
7
7
% A
% Cys:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
7
27
0
0
0
0
0
0
0
% D
% Glu:
7
0
0
0
0
0
0
7
0
7
54
0
7
7
7
% E
% Phe:
0
14
0
7
0
0
14
0
0
0
0
0
0
0
0
% F
% Gly:
0
40
0
0
0
0
0
0
0
0
0
0
0
0
14
% G
% His:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
7
0
14
0
0
0
14
7
0
% I
% Lys:
34
0
0
14
7
7
0
0
0
14
14
0
0
34
34
% K
% Leu:
0
0
74
7
7
0
0
14
0
7
0
0
67
14
0
% L
% Met:
0
0
14
7
0
0
0
0
0
0
7
14
7
0
7
% M
% Asn:
0
7
0
7
7
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
20
0
0
0
0
0
20
0
0
0
0
80
0
0
0
% Q
% Arg:
40
0
0
20
67
0
14
7
7
74
0
0
0
20
20
% R
% Ser:
0
20
0
0
7
7
7
0
0
0
14
0
0
7
14
% S
% Thr:
0
0
0
0
0
0
7
27
0
0
0
0
0
0
0
% T
% Val:
0
0
0
27
0
7
0
14
67
0
0
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _