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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX35
All Species:
28.48
Human Site:
Y184
Identified Species:
44.76
UniProt:
Q9H5Z1
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H5Z1
NP_068750.2
703
78910
Y184
E
A
H
E
R
T
L
Y
T
D
I
A
I
G
L
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
I422
I
A
N
H
Q
V
L
I
I
E
G
E
T
G
S
Rhesus Macaque
Macaca mulatta
XP_001088680
703
78826
Y184
E
A
H
E
R
T
L
Y
T
D
I
A
I
G
L
Dog
Lupus familis
XP_542996
769
85800
Y184
E
A
H
E
R
T
L
Y
T
D
I
A
I
G
L
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
I611
D
N
Q
I
L
I
V
I
G
E
T
G
S
G
K
Rat
Rattus norvegicus
Q5XI69
779
88496
T181
E
A
H
E
R
T
L
T
T
D
I
L
F
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512863
703
79017
Y184
E
A
H
E
R
T
L
Y
T
D
I
A
I
G
L
Chicken
Gallus gallus
XP_417352
703
78661
Y184
E
A
H
E
R
T
L
Y
T
D
I
A
I
G
L
Frog
Xenopus laevis
Q5XH12
748
85094
S195
D
V
Y
E
R
F
V
S
T
D
V
L
L
S
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396598
671
75928
G169
L
L
T
D
I
I
M
G
L
L
K
K
I
I
R
Nematode Worm
Caenorhab. elegans
Q9BKQ8
732
82525
N206
E
A
H
E
R
S
C
N
T
D
I
L
L
G
L
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
XP_002305762
702
78145
S182
E
A
H
E
R
S
I
S
T
D
I
L
L
G
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
M633
L
S
Q
Y
S
V
I
M
L
D
E
A
H
E
R
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
N463
E
W
E
K
N
R
M
N
E
S
I
S
Y
G
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.6
98.2
88.1
N.A.
26.5
34.4
N.A.
90.9
90
27.8
N.A.
N.A.
N.A.
53.6
51.3
32.4
Protein Similarity:
100
44.1
99
89.8
N.A.
39
53.4
N.A.
96.7
95.8
49
N.A.
N.A.
N.A.
72.5
70.9
46.6
P-Site Identity:
100
20
100
100
N.A.
6.6
80
N.A.
100
100
26.6
N.A.
N.A.
N.A.
6.6
66.6
0
P-Site Similarity:
100
40
100
100
N.A.
26.6
80
N.A.
100
100
60
N.A.
N.A.
N.A.
20
80
0
Percent
Protein Identity:
49
N.A.
N.A.
25.8
28.2
N.A.
Protein Similarity:
68.2
N.A.
N.A.
39.9
42
N.A.
P-Site Identity:
66.6
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
86.6
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
0
0
0
0
0
0
0
0
0
40
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
0
7
0
0
0
0
0
67
0
0
0
0
0
% D
% Glu:
60
0
7
60
0
0
0
0
7
14
7
7
0
7
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
7
0
7
% F
% Gly:
0
0
0
0
0
0
0
7
7
0
7
7
0
74
0
% G
% His:
0
0
54
7
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
7
0
0
7
7
14
14
14
7
0
60
0
40
7
0
% I
% Lys:
0
0
0
7
0
0
0
0
0
0
7
7
0
0
14
% K
% Leu:
14
7
0
0
7
0
47
0
14
7
0
27
20
0
54
% L
% Met:
0
0
0
0
0
0
14
7
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
0
7
0
0
14
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
14
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
60
7
0
0
0
0
0
0
0
0
14
% R
% Ser:
0
7
0
0
7
14
0
14
0
7
0
7
7
7
7
% S
% Thr:
0
0
7
0
0
40
0
7
60
0
7
0
7
0
0
% T
% Val:
0
7
0
0
0
14
14
0
0
0
7
0
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
0
0
0
34
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _